Research workbench
Resting state full-length GLUA1/A2 heterotertramer in complex with tarp gamma 8 and CNIH2
Analyse Resting state full-length GLUA1/A2 heterotertramer in complex with tarp gamma 8… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7OCA
- Type
- protein
- Length
- 3,802 residues
- Chains
- 8
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P19490, P19491, Q5BJU5, Q8VHW5
- Ligands
- PC1, E2Q, CLR, NAG, BMA
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | — | protein | 775 | — | P19490 |
| B, D | — | protein | 783 | — | P19491 |
| G, E | — | protein | 158 | — | Q5BJU5 |
| I, J | — | protein | 185 | — | Q8VHW5 |
Ligands and binding sites
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · ligand · 46 copies · chains A, B, G, D, I, C, J, E
- E2Q · 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide · ligand · 4 copies · chains A, B, D, C
- CLR · Cholesterol · ligand · 2 copies · chains G, E
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 18 copies · chains A, D, B, C
- BMA · beta-D-mannopyranose · sugar · 2 copies
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7OCA · Resting state full-length GluA1/A2 heterotertramer in complex with TARP gamma 8 and CNIH2 · the same entry in another collection · chain E against E, TM-score 1.00
- Q8VHW5 · AlphaFold monomer V2.0 prediction for voltage-dependent calcium channel gamma-8 subunit… · a predicted model of the same protein · chain I against A, TM-score 0.96
- Q5BJU5 · AlphaFold monomer V2.0 prediction for protein cornichon homolog 2 (Q5BJU5) · a predicted model of the same protein · chain E against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19490
- Every structure of UniProt P19491
- Every structure of UniProt Q5BJU5
- Every structure of UniProt Q8VHW5
- Elsewhere: RCSB PDB 7OCA · PDBe 7OCA · UniProt P19490 · UniProt P19491 · UniProt Q5BJU5 · UniProt Q8VHW5
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