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UniProt Q5BJU5

Protein cornichon homolog 2 (Q5BJU5)

Protein cornichon homolog 2 (UniProt Q5BJU5): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
Q5BJU5
Protein
Protein cornichon homolog 2
Experimental structures
6
Predicted models
1
Ligands
2
Pockets
8 · 3 records with a druggable one

Structures

7 records of Q5BJU5 in the MolNFT archive: 6 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7OCAResting state full-length GluA1/A2 heterotertramer in complex with TARP gamma 8 and CNIH2electron microscopyG, EPC1, CLR2 (best 0.61)
7OCAResting state full-length GLUA1/A2 heterotertramer in complex with tarp gamma 8 and CNIH2electron microscopyG, EPC1, CLR—
7OCEResting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)electron microscopyG, EPC1, CLR2 (best 0.63)
7OCEResting state GLUA1/A2 AMPA receptor in complex with tarp gamma 8 and CNIH2 (lbd-tmd)electron microscopyG, EPC1, CLR—
7OCFActive state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)electron microscopyG, EPC14 (best 0.65)
7OCFActive state GLUA1/A2 AMPA receptor in complex with tarp gamma 8 and CNIH2 (lbd-tmd)electron microscopyG, EPC1—
Q5BJU5AlphaFold monomer V2.0 prediction for protein cornichon homolog 2 (Q5BJU5)predictedA——

Ligands

  • PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 6 records
  • CLR · Cholesterol · in 4 records

Experiment against prediction

Elsewhere

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