UniProt Q6B856
Tubulin beta-2B chain (Q6B856)
Tubulin beta-2B chain (UniProt Q6B856): 399 experimental structures on GenesisL1, 168 ligands bound, 1,449 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q6B856
- Protein
- Tubulin beta-2B chain
- Experimental structures
- 399
- Predicted models
- 0
- Ligands
- 168
- Pockets
- 1,449 · 118 records with a druggable one
Structures
399 records of Q6B856 in the MolNFT archive: 399 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XRP | Human Doublecortin N-DC Repeat (1MJD) and Mammalian Tubulin (1JFF and 3HKE) Docked into the… | electron microscopy | A, C, E, G | — | — |
| 2XRP | Human doublecortin N-dc repeat (1MJD) and mammalian tubulin (1JFF and 3HKE) docked into the… | electron microscopy | A, C, E, G | — | — |
| 3DU7 | Tubulin-colchicine-phomopsin A: Stathmin-like domain complex | x-ray diffraction | B, D | — | — |
| 3DU7 | Tubulin-colchicine-phomopsin a: stathmin-like domain complex | x-ray diffraction | B, D | — | — |
| 3E22 | Tubulin-colchicine-soblidotin: Stathmin-like domain complex | x-ray diffraction | B, D | — | — |
| 3E22 | Tubulin-colchicine-soblidotin: stathmin-like domain complex | x-ray diffraction | B, D | — | — |
| 3J2U | Kinesin-13 KLP10A HD in complex with CS-tubulin and a microtubule | electron microscopy | B, D | — | — |
| 3J2U | Kinesin-13 KLP10A hd in complex with cs-tubulin and a microtubule | electron microscopy | B, D | — | — |
| 4AQV | Model of human kinesin-5 motor domain (3HQD) and mammalian tubulin heterodimer (1JFF) docked into… | electron microscopy | B | — | — |
| 4AQV | Model of human kinesin-5 motor domain (3HQD) and mammalian tubulin heterodimer (1JFF) docked into… | electron microscopy | B | — | — |
| 4AQW | Model of human kinesin-5 motor domain (1II6, 3HQD) and mammalian tubulin heterodimer (1JFF) docked… | electron microscopy | B | — | — |
| 4AQW | 4aqw | electron microscopy | B | — | — |
| 4ATU | Human doublecortin N-DC repeat plus linker, and tubulin (2XRP) docked into an 8A cryo-EM map of… | electron microscopy | A, C, E, G | — | — |
| 4ATU | Human doublecortin N-dc repeat plus linker, and tubulin (2XRP) docked into an 8A cryo-EM MAP of… | electron microscopy | A, C, E, G | — | — |
| 4ATX | Rigor kinesin motor domain with an ordered neck-linker, docked on tubulin dimer, modelled into the… | electron microscopy | A | — | — |
| 4ATX | Rigor kinesin motor domain with an ordered neck-linker, docked on tubulin dimer, modelled into the… | electron microscopy | A | — | — |
| 4CK5 | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP state, based on… | electron microscopy | B | — | — |
| 4CK5 | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP state, based on… | electron microscopy | B | — | — |
| 4CK6 | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP.AlFx state, based… | electron microscopy | B | — | — |
| 4CK6 | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP.ALFX state, based… | electron microscopy | B | — | — |
| 4CK7 | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in presence of adp.alfx… | electron microscopy | B | — | — |
| 4CK7 | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in presence of ADP.ALFX… | electron microscopy | B | — | — |
| 4I4T | Crystal structure of tubulin-RB3-TTL-Zampanolide complex | x-ray diffraction | B, D | — | — |
| 4I4T | Crystal structure of tubulin-RB3-ttl-zampanolide complex | x-ray diffraction | B, D | — | — |
| 4I50 | Crystal structure of tubulin-stathmin-TTL-Epothilone A complex | x-ray diffraction | B, D | — | — |
| 4I50 | Crystal structure of tubulin-stathmin-ttl-epothilone a complex | x-ray diffraction | B, D | — | — |
| 4I55 | Crystal structure of tubulin-stathmin-TTL complex | x-ray diffraction | B, D | — | — |
| 4I55 | Crystal structure of tubulin-stathmin-ttl complex | x-ray diffraction | B, D | — | — |
| 4IHJ | Crystal structure of tubulin-stathmin-TTL-ADP complex | x-ray diffraction | B, D | — | — |
| 4IHJ | Crystal structure of tubulin-stathmin-ttl-ADP complex | x-ray diffraction | B, D | — | — |
| 4IIJ | Crystal structure of tubulin-stathmin-TTL-apo complex | x-ray diffraction | B, D | — | — |
| 4IIJ | Crystal structure of tubulin-stathmin-ttl-apo complex | x-ray diffraction | B, D | — | — |
| 4O2A | Tubulin-BAL27862 complex | x-ray diffraction | B, D | — | — |
| 4O2A | Tubulin-BAL27862 complex | x-ray diffraction | B, D | — | — |
| 4O2B | Tubulin-Colchicine complex | x-ray diffraction | B, D | — | — |
| 4O2B | Tubulin-colchicine complex | x-ray diffraction | B, D | — | — |
| 4O4H | Tubulin-Laulimalide complex | x-ray diffraction | B, D | — | — |
| 4O4H | Tubulin-laulimalide complex | x-ray diffraction | B, D | — | — |
| 4O4I | Tubulin-Laulimalide-Epothilone A complex | x-ray diffraction | B, D | — | — |
| 4O4I | Tubulin-laulimalide-epothilone a complex | x-ray diffraction | B, D | — | — |
| 4O4J | Tubulin-Peloruside A complex | x-ray diffraction | B, D | — | — |
| 4O4J | Tubulin-peloruside a complex | x-ray diffraction | B, D | — | — |
| 4O4L | Tubulin-Peloruside A-Epothilone A complex | x-ray diffraction | B, D | — | — |
| 4O4L | Tubulin-peloruside a-epothilone a complex | x-ray diffraction | B, D | — | — |
| 4TUY | Tubulin-Rhizoxin complex | x-ray diffraction | B, D | — | — |
| 4TUY | Tubulin-rhizoxin complex | x-ray diffraction | B, D | — | — |
| 4TV8 | Tubulin-Maytansine complex | x-ray diffraction | B, D | — | — |
| 4TV8 | Tubulin-maytansine complex | x-ray diffraction | B, D | — | — |
| 4TV9 | Tubulin-PM060184 complex | x-ray diffraction | B, D | — | — |
| 4TV9 | Tubulin-PM060184 complex | x-ray diffraction | B, D | — | — |
| 4UXO | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in… | electron microscopy | B | — | — |
| 4UXO | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in… | electron microscopy | B | — | — |
| 4UXP | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in… | electron microscopy | B | — | — |
| 4UXP | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in… | electron microscopy | B | — | — |
| 4UXR | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in… | electron microscopy | B | — | — |
| 4UXR | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in… | electron microscopy | B | — | — |
| 4UXS | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in… | electron microscopy | B | — | — |
| 4UXS | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in… | electron microscopy | B | — | — |
| 4UXT | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in… | electron microscopy | B | — | — |
| 4UXT | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in… | electron microscopy | B | — | — |
339 records more on the page itself.
Ligands
- GDP · Guanosine-5'-diphosphate · in 306 records
- GTP · Guanosine-5'-triphosphate · in 291 records
- MG · Magnesium ion · in 279 records
- CA · Calcium ion · in 177 records
- TA1 · Taxol · in 27 records
- IBL · Azo-Combretastatin A4 (cis) · in 7 records
- LOC · N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide · in 6 records
- VLB · (2alpha,2'beta,3beta,4alpha,5beta)-vincaleukoblastine · in 5 records
- VYT · Azo-Combretastatin A4 (trans) · in 5 records
- 4I2 · N-(4-{2-[3-(trifluoromethyl)anilino]-1,3-thiazol-4-yl}phenyl)acetamide · in 4 records
- 8WB · 2-methoxy-5-(2,3,4-trimethoxyphenyl)cyclohepta-2,4,6-trien-1-one · in 4 records
- BKF · (1S,2S,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3, 5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl 2-methylpropanoate · in 3 records
- I8R · 2-methoxy-5-[2-(5,6,7-trimethoxy-1,3-benzothiazol-2-yl)ethyl]phenol · in 3 records
- PO4 · Phosphate ion · in 3 records
- 2GE · N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine · in 2 records
- 47F · N-[4-(2-anilino-1,3-thiazol-4-yl)phenyl]acetamide · in 2 records
- 4B6 · N-{4-[2-(2-fluoroanilino)-1,3-thiazol-4-yl]phenyl}acetamide · in 2 records
- 5JH · (1R,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3, 5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl heptanoate · in 2 records
- 6NL · (2E)-3-(3-hydroxy-4-methoxyphenyl)-1-(7-methoxy-2H-1,3-benzodioxol-5-yl)-2-methylprop-2-en-1-one · in 2 records
- 71P · ~{N}-[(7~{R})-1,2,3-trimethoxy-10-methylsulfanyl-9-oxidanylidene-6,7-dihydro-5~{H}-benzo[a]heptalen-7-yl]ethanamide · in 2 records
- 7AK · (+)-Discodermolide · in 2 records
- 7AO · [(3~{Z},5~{S},6~{S},7~{S},8~{R},9~{S},11~{Z},13~{S}, 14~{S},15~{S},16~{Z},18~{S})-19-[(2~{S},3~{R},4~{S}, 5~{R})-3,5-dimethyl-4-oxidanyl-6-oxidanylidene-oxan-2-yl]-5,7,9,11,13,15-hexamethyl-8,14,18-tris(oxidanyl) nonadeca-1,3,11,16-tetraen-6-yl] ~{N}-[3-[(3-azidophenyl)carbonylamino]propyl]carbamate · in 2 records
- 7BA · Combretastatin A4 · in 2 records
- 7LZ · (3~{Z},5~{E},7~{R},8~{S},10~{S},11~{Z},13~{S},14~{R}, 15~{S},17~{S},20~{R},21~{S},22~{S})-22-[(2~{S},3~{Z})-hexa-3,5-dien-2-yl]-7,13,15,17,21-pentamethyl-8,10,14, 20-tetrakis(oxidanyl)-1-oxacyclodocosa-3,5,11-trien-2-one · in 2 records
- 84F · (3S,4R)-4-(3-hydroxy-4-methoxyphenyl)-3-methyl-1-(3,4, 5-trimethoxyphenyl)azetidin-2-one · in 2 records
- 89O · (5S,5aR,8aR,9R)-9-(3,5-dimethoxy-4-oxidanyl-phenyl)-5-oxidanyl-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one · in 2 records
- 89U · 10-[(4-methoxy-3-oxidanyl-phenyl)methylidene]anthracen-9-one · in 2 records
- 8WE · (2~{Z},4~{E})-~{N}-[(~{S})-oxidanyl-[(1~{S},2~{E}, 5~{S},11~{R},17~{S},19~{R})-3,11,19-trimethyl-7,13-bis(oxidanylidene)-6,21-dioxabicyclo[15.3.1]henicos-2-en-5-yl]methyl]hexa-2,4-dienamide · in 2 records
- 8Z8 · 5-chloranyl-7-[(1~{R},5~{S})-3-methoxy-8-azabicyclo[3.2.1]octan-8-yl]-6-[2,4,6-tris(fluoranyl) phenyl]-[1,2,4]triazolo[1,5-a]pyrimidine · in 2 records
- 918 · 5-(2-morpholin-4-yl-6-pyrrolidin-1-yl-pyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine · in 2 records
Elsewhere
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