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Ligand · TZT

TZT · Soblidotin

TZT, Soblidotin (C39 H67 N5 O6, 702.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
TZT
Formula
C39 H67 N5 O6
Class
ligand
Structures
2
PDB entries
1

Binding sites

TZT in 2 structures; the first of them:

  • 3E22 · Tubulin-colchicine-soblidotin: Stathmin-like domain complex · TZT B800 · binds GLN11, GLN15, THR74, SER77, VAL177, SER178, ASP179, THR221 and 11 more
  • 3E22 · Tubulin-colchicine-soblidotin: stathmin-like domain complex · TZT B800 · binds GLN11, GLN15, THR74, SER77, VAL177, SER178, ASP179, THR221 and 11 more

Residues it binds most

THR 2, VAL 2, ASN 2, GLN 2, PRO 2, SER 2, ASP 2, GLY 2, LEU 2, PHE 2 (residue and the binding sites it lines).

Found with

  • GDP · Guanosine-5'-diphosphate
  • GTP · Guanosine-5'-triphosphate
  • LOC · N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide
  • MG · Magnesium ion

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