UniProt Q13148
TAR DNA-binding protein 43 (Q13148)
TAR DNA-binding protein 43 (UniProt Q13148): 62 experimental structures on GenesisL1, 1 ligand bound, 19 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q13148
- Protein
- TAR DNA-binding protein 43
- Experimental structures
- 62
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 19 · 3 records with a druggable one
Structures
62 records of Q13148 in the MolNFT archive: 62 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WF0 | Solution structure of RRM domain in TAR DNA-binding protein-43 | solution nmr | A | — | — |
| 1WF0 | Solution structure of rrm domain in tar DNA-binding protein-43 | solution nmr | A | — | — |
| 2CQG | Solution structure of the RNA binding domain of TAR DNA-binding protein-43 | solution nmr | A | — | — |
| 2CQG | Solution structure of the RNA binding domain of tar DNA-binding protein-43 | solution nmr | A | — | — |
| 2N2C | NMR Structure of TDP-43 prion-like hydrophobic helix in DPC | solution nmr | A | — | — |
| 2N2C | NMR structure of tdp-43 prion-like hydrophobic helix in dpc | solution nmr | A | — | — |
| 2N3X | Solution Structure of TDP-43 Amyloidogenic Core Region | solution nmr | A | — | — |
| 2N3X | Solution structure of tdp-43 amyloidogenic core region | solution nmr | A | — | — |
| 2N4G | Solution Structure of the G335D Mutant of TDP-43 Amyloidogenic Core Region | solution nmr | A | — | — |
| 2N4G | Solution structure of the G335D mutant of tdp-43 amyloidogenic core region | solution nmr | A | — | — |
| 2N4H | Solution Structure of the Q343R Mutant of TDP-43 Amyloidogenic Core Region | solution nmr | A | — | — |
| 2N4H | Solution structure of the Q343R mutant of tdp-43 amyloidogenic core region | solution nmr | A | — | — |
| 2N4P | Solution structure of the n-terminal domain of tdp-43 | solution nmr | A | — | — |
| 2N4P | Solution structure of the N-terminal domain of tdp-43 | solution nmr | A | — | — |
| 4BS2 | NMR structure of human TDP-43 tandem RRMs in complex with UG-rich RNA | solution nmr | A | — | — |
| 4BS2 | NMR structure of human tdp-43 tandem rrms in complex with ug-rich RNA | solution nmr | A | — | — |
| 4IUF | Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA | x-ray diffraction | A | — | — |
| 4IUF | Crystal structure of human tdp-43 RRM1 domain in complex with a single-stranded DNA | x-ray diffraction | A | — | — |
| 4Y00 | Crystal Structure of Human TDP-43 RRM1 Domain with D169G Mutation in Complex with an Unmodified… | x-ray diffraction | A, B, C, D | — | — |
| 4Y00 | Crystal structure of human tdp-43 RRM1 domain with D169G mutation in complex with an unmodified… | x-ray diffraction | A, B, C, D | — | — |
| 4Y0F | Crystal Structure of Human TDP-43 RRM1 Domain in Complex with an Unmodified Single-stranded DNA | x-ray diffraction | A, B | — | — |
| 4Y0F | Crystal structure of human tdp-43 RRM1 domain in complex with an unmodified single-stranded DNA | x-ray diffraction | A, B | — | — |
| 5MRG | Solution structure of TDP-43 (residues 1-102) | solution nmr | A | — | 1 (best 0.50) |
| 5MRG | Solution structure of tdp-43 (residues 1-102) | solution nmr | A | — | — |
| 5W50 | Crystal structure of the segment, liikgi, from the RRM2 of tdp-43, residues 248-253 | x-ray diffraction | A, B | — | — |
| 5W52 | MicroED structure of the segment, DLIIKGISVHI, from the RRM2 of TDP-43, residues 247-257 | electron crystallography | A | — | — |
| 5W52 | Microed structure of the segment, dliikgisvhi, from the RRM2 of tdp- 43, residues 247-257 | electron crystallography | A | — | — |
| 5W7V | CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril | electron microscopy | 1, 3, 2, 6, 5, 4, 7, 0, 8 | — | — |
| 5W7V | Cryoem structure of the segment, dliikgisvhi, assembled into a triple- helical fibril | electron microscopy | 1, 3, 2, 6, 5, 4, 7, 0, 8 | — | — |
| 5WHN | Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317 | x-ray diffraction | A | — | — |
| 5WHN | Crystal structure of the segment, nfgafs, from the low complexity domain of tdp-43, residues 312-317 | x-ray diffraction | A | — | — |
| 5WHP | Crystal structure of the segment, nfgtfs, from the A315T familial variant of the low complexity… | x-ray diffraction | A | — | — |
| 5WIA | Crystal structure of the segment, gnnsys, from the low complexity domain of tdp-43, residues 370-375 | x-ray diffraction | A | — | — |
| 5WIQ | Crystal structure of the segment, GFNGGFG, from the low complexity domain of TDP-43, residues… | x-ray diffraction | A, B | — | — |
| 5WIQ | Crystal structure of the segment, gfnggfg, from the low complexity domain of tdp-43, residues… | x-ray diffraction | A, B | — | — |
| 5WKB | MicroED structure of the segment, NFGEFS, from the A315E familial variant of the low complexity… | electron crystallography | A | — | — |
| 5WKB | Microed structure of the segment, nfgefs, from the A315E familial variant of the low complexity… | electron crystallography | A | — | — |
| 5WKD | Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues… | x-ray diffraction | A | — | — |
| 5WKD | Crystal structure of the segment, gnnqgsn, from the low complexity domain of tdp-43, residues… | x-ray diffraction | A | — | — |
| 5X4F | Solution Structure of the N-terminal Domain of TDP-43 | solution nmr | A | — | 2 (best 0.35) |
| 5X4F | Solution structure of the N-terminal domain of tdp-43 | solution nmr | A | — | — |
| 6B1G | Solution structure of TDP-43 N-terminal domain dimer. | solution nmr | A, B | — | — |
| 6B1G | Solution structure of tdp-43 N-terminal domain dimer. | solution nmr | A, B | — | — |
| 6CFH | SWGMMGMLASQ segment from the low complexity domain of TDP-43 | electron crystallography | A, B | — | — |
| 6CFH | Swgmmgmlasq segment from the low complexity domain of tdp-43 | electron crystallography | A, B | — | — |
| 6N37 | SegA-sym, conformation of TDP-43 low complexity domain segment A sym | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | — |
| 6N37 | Sega-sym, conformation of tdp-43 low complexity domain segment a sym | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | — |
| 6N3A | Sega-long, conformation of tdp-43 low complexity domain segment a long | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | — |
| 6N3B | SegA-asym, conformation of TDP-43 low complexity domain segment A asym | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | — |
| 6N3B | Sega-asym, conformation of tdp-43 low complexity domain segment a asym | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | — |
| 6N3C | Segb, conformation of tdp-43 low complexity domain segment a | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 6T4B | Crystal structure of human tdp-43 N-terminal domain at 2.55 a resolution | x-ray diffraction | A, C, E, G, I | SO4 | 5 (best 0.41) |
| 6T4B | Crystal structure of human tdp-43 N-terminal domain at 2.55 a resolution | x-ray diffraction | A, C, E, G, I | SO4 | — |
| 7KWZ | Tdp-43 lcd amyloid fibrils | electron microscopy | A, B, C, D, E | — | — |
| 7N9H | Structure of the mammalian importin A1 bound to the tdp-43 nls | x-ray diffraction | A | — | — |
| 7PY2 | Structure of pathological tdp-43 filaments from als with ftld | electron microscopy | A, B, C, D | — | — |
| 8A6I | Structure of the low complexity domain of TDP-43 (fragment 309-350) with methionine sulfoxide… | solution nmr | A | — | — |
| 8CG3 | Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1) | electron microscopy | U, A, B, C, D | — | 4 (best 0.77) |
| 8CGG | Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 2) | electron microscopy | U, A, B, C, D | — | 1 (best 0.63) |
| 8QXA | TDP-43 amyloid fibrils: Morphology-1b | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | — | 4 (best 0.48) |
2 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 2 records
Elsewhere
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