MolNFT v1 · #143498 · protein

Solution structure of tdp-43 N-terminal domain dimer.

6B1G · Tar DNA-binding protein 43, S48E mutant: “Solution structure of tdp-43 N-terminal domain dimer.”. Solution nmr. MolNFT v1 #143498 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6B1G
Type: protein
Length: 160 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tar DNA-binding protein 43, S48E mutant; Tar DNA-binding protein 43, Y4R mutant
UniProt: Q13148

Structure

solution nmr · 2 distinct chains · 8% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tar DNA-binding protein 43, S48E mutant	protein	80	9% helix, 38% strand	Q13148
B	Tar DNA-binding protein 43, Y4R mutant	protein	80	6% helix, 39% strand	Q13148

Interfaces

1 interface between chains.

A–B · 773 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

6B1G · Solution structure of TDP-43 N-terminal domain dimer. · the same entry in another collection · chain A against A, TM-score 1.00
Q13148 · AlphaFold monomer V2.0 prediction for tar DNA-binding protein 43 (Q13148) · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13148
Elsewhere: RCSB PDB 6B1G · PDBe 6B1G · UniProt Q13148

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