MolNFT v1 · #95583 · protein + DNA
Crystal structure of human tdp-43 RRM1 domain in complex with a single-stranded DNA
4IUF · Tar DNA-binding protein 43: “Crystal structure of human tdp-43 RRM1 domain in complex with a single-stranded DNA”. X-ray diffraction. MolNFT v1 #95583 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4IUF
- Type
- protein + DNA
- Length
- 86 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tar DNA-binding protein 43; 5'-D(*GP*TP*TP*GP*(XUA)P*GP*CP*GP*T)-3'
- UniProt
- Q13148
Structure
x-ray diffraction · 2 distinct chains · 22% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tar DNA-binding protein 43 | protein | 77 | 22% helix, 39% strand | Q13148 |
| B | 5'-D(*GP*TP*TP*GP*(XUA)P*GP*CP*GP*T)-3' | dna | 9 | — | — |
Interfaces
1 interface between chains.
- A–B · 745 Ų buried · 15 hydrogen bonds · protein-nucleic
Modifications
Observed in the structure: 1 modified (nucleotide modification).
Compared structures
- 4IUF · Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA · the same entry in another collection · chain A against A, TM-score 1.00
- Q13148 · AlphaFold monomer V2.0 prediction for tar DNA-binding protein 43 (Q13148) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13148
- Elsewhere: RCSB PDB 4IUF · PDBe 4IUF · UniProt Q13148
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