MolNFT v1 · #181584 · protein
Tubulin-RB3_SLD-ttl in complex with compound 5T
7LZ8: “Tubulin-RB3_SLD-ttl in complex with compound 5T”. X-ray diffraction, 7 ligands (GTP, YJ4, GDP). MolNFT v1 #181584 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LZ8
- Type
- protein
- Length
- 2,093 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q2XVP4, A0A287AGU7, P63043, E1BQ43
- Ligands
- GTP, YJ4, GDP, ACP, CA, MG, CL
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 437 | — | Q2XVP4 |
| B | — | protein | 424 | — | A0A287AGU7 |
| C | — | protein | 438 | — | Q2XVP4 |
| D | — | protein | 417 | — | A0A287AGU7 |
| E | — | protein | 121 | — | P63043 |
| F | — | protein | 256 | — | E1BQ43 |
Ligands and binding sites
- GTP · Guanosine-5'-triphosphate · ligand · 3 copies · chains A, C, D
- YJ4 · 4-[2-(ethylamino)pyrido[3,2-d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one · ligand · 2 copies · chains A, B, C, D
- GDP · Guanosine-5'-diphosphate · ligand · chains B
- ACP · Phosphomethylphosphonic acid adenylate ester · ligand · chains F
- CA · Calcium ion · metal · 4 copies · chains A, B, C
- MG · Magnesium ion · metal · 4 copies · chains B, C, D
- CL · Chloride ion · ion · 2 copies · chains A, D
- MES · 2-(N-morpholino)-ethanesulfonic acid · additive · 2 copies · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2XVP4
- Every structure of UniProt A0A287AGU7
- Every structure of UniProt P63043
- Every structure of UniProt E1BQ43
- Elsewhere: RCSB PDB 7LZ8 · PDBe 7LZ8 · UniProt Q2XVP4 · UniProt A0A287AGU7 · UniProt P63043 · UniProt E1BQ43
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.