Tubulin-RB3_SLD-ttl in complex with compound 5T

Structure

x-ray diffraction · 6 distinct chains.

Ligands and binding sites

• GTP · Guanosine-5'-triphosphate · ligand · 3 copies · chains A, C, D
• YJ4 · 4-[2-(ethylamino)pyrido[3,2-d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one · ligand · 2 copies · chains A, B, C, D
• GDP · Guanosine-5'-diphosphate · ligand · chains B
• ACP · Phosphomethylphosphonic acid adenylate ester · ligand · chains F
• CA · Calcium ion · metal · 4 copies · chains A, B, C
• MG · Magnesium ion · metal · 4 copies · chains B, C, D
• CL · Chloride ion · ion · 2 copies · chains A, D
• MES · 2-(N-morpholino)-ethanesulfonic acid · additive · 2 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7LZ8 · Tubulin-RB3_SLD-TTL in complex with compound 5t · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q2XVP4
• Every structure of UniProt A0A287AGU7
• Every structure of UniProt P63043
• Every structure of UniProt E1BQ43
• Elsewhere: RCSB PDB 7LZ8 · PDBe 7LZ8 · UniProt Q2XVP4 · UniProt A0A287AGU7 · UniProt P63043 · UniProt E1BQ43