UniProt E1BQ43
Tubulin-tyrosine ligase (E1BQ43)
Tubulin-tyrosine ligase (UniProt E1BQ43): 441 experimental structures on GenesisL1, 4 ligands bound, 1,198 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- E1BQ43
- Protein
- Tubulin-tyrosine ligase
- Experimental structures
- 441
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 1,198 · 223 records with a druggable one
Structures
441 records of E1BQ43 in the MolNFT archive: 441 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4I4T | Crystal structure of tubulin-RB3-TTL-Zampanolide complex | x-ray diffraction | F | MG, ACP | 5 (best 0.81) |
| 4I4T | Crystal structure of tubulin-RB3-ttl-zampanolide complex | x-ray diffraction | F | — | — |
| 4I50 | Crystal structure of tubulin-stathmin-TTL-Epothilone A complex | x-ray diffraction | F | ACP, MG | 7 (best 0.80) |
| 4I50 | Crystal structure of tubulin-stathmin-ttl-epothilone a complex | x-ray diffraction | F | — | — |
| 4I55 | Crystal structure of tubulin-stathmin-TTL complex | x-ray diffraction | F | MG, ACP | 5 (best 0.82) |
| 4I55 | Crystal structure of tubulin-stathmin-ttl complex | x-ray diffraction | F | — | — |
| 4IHJ | Crystal structure of tubulin-stathmin-TTL-ADP complex | x-ray diffraction | F | MG, ADP | 5 (best 0.82) |
| 4IHJ | Crystal structure of tubulin-stathmin-ttl-ADP complex | x-ray diffraction | F | — | — |
| 4IIJ | Crystal structure of tubulin-stathmin-TTL-apo complex | x-ray diffraction | F | MG | 4 (best 0.81) |
| 4IIJ | Crystal structure of tubulin-stathmin-ttl-apo complex | x-ray diffraction | F | — | — |
| 4O2A | Tubulin-BAL27862 complex | x-ray diffraction | F | ADP | 5 (best 0.88) |
| 4O2A | Tubulin-BAL27862 complex | x-ray diffraction | F | — | — |
| 4O2B | Tubulin-Colchicine complex | x-ray diffraction | F | MG, ACP | 6 (best 0.87) |
| 4O2B | Tubulin-colchicine complex | x-ray diffraction | F | — | — |
| 4O4H | Tubulin-Laulimalide complex | x-ray diffraction | F | ACP, MG | 5 (best 0.82) |
| 4O4H | Tubulin-laulimalide complex | x-ray diffraction | F | — | — |
| 4O4I | Tubulin-Laulimalide-Epothilone A complex | x-ray diffraction | F | ACP, MG | 6 (best 0.80) |
| 4O4I | Tubulin-laulimalide-epothilone a complex | x-ray diffraction | F | — | — |
| 4O4J | Tubulin-Peloruside A complex | x-ray diffraction | F | ACP | 6 (best 0.81) |
| 4O4J | Tubulin-peloruside a complex | x-ray diffraction | F | — | — |
| 4O4L | Tubulin-Peloruside A-Epothilone A complex | x-ray diffraction | F | — | 4 (best 0.82) |
| 4O4L | Tubulin-peloruside a-epothilone a complex | x-ray diffraction | F | — | — |
| 4TUY | Tubulin-Rhizoxin complex | x-ray diffraction | F | ACP, MG | 5 (best 0.77) |
| 4TUY | Tubulin-rhizoxin complex | x-ray diffraction | F | — | — |
| 4TV8 | Tubulin-Maytansine complex | x-ray diffraction | F | ACP | 6 (best 0.79) |
| 4TV8 | Tubulin-maytansine complex | x-ray diffraction | F | — | — |
| 4TV9 | Tubulin-PM060184 complex | x-ray diffraction | F | ACP, MG | 5 (best 0.78) |
| 4TV9 | Tubulin-PM060184 complex | x-ray diffraction | F | — | — |
| 4YJ2 | Crystal structure of tubulin bound to MI-181 | x-ray diffraction | F | — | 6 (best 0.85) |
| 4YJ2 | Crystal structure of tubulin bound to mi-181 | x-ray diffraction | F | — | — |
| 4YJ3 | Crystal structure of tubulin bound to compound 2 | x-ray diffraction | F | — | 5 (best 0.83) |
| 4YJ3 | Crystal structure of tubulin bound to compound 2 | x-ray diffraction | F | — | — |
| 4ZHQ | Crystal structure of Tubulin-Stathmin-TTL-MMAE Complex | x-ray diffraction | F | ACP | 6 (best 0.81) |
| 4ZHQ | Crystal structure of tubulin-stathmin-ttl-mmae complex | x-ray diffraction | F | — | — |
| 4ZI7 | Crystal structure of tubulin-stathmin-ttl-HTI286 complex | x-ray diffraction | F | ACP | 6 (best 0.77) |
| 4ZI7 | Crystal structure of tubulin-stathmin-ttl-HTI286 complex | x-ray diffraction | F | — | — |
| 4ZOL | Crystal Structure of Tubulin-Stathmin-TTL-Tubulysin M Complex | x-ray diffraction | F | ACP | 5 (best 0.84) |
| 4ZOL | Crystal structure of tubulin-stathmin-ttl-tubulysin M complex | x-ray diffraction | F | — | — |
| 5BMV | CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-Vinblastine COMPLEX | x-ray diffraction | F | ACP | 6 (best 0.81) |
| 5BMV | Crystal structure of tubulin-stathmin-ttl-vinblastine complex | x-ray diffraction | F | — | — |
| 5C8Y | Crystal structure of T2R-TTL-Plinabulin complex | x-ray diffraction | F | ACP | 6 (best 0.83) |
| 5C8Y | Crystal structure of T2R-ttl-plinabulin complex | x-ray diffraction | F | — | — |
| 5CA0 | Crystal structure of T2R-TTL-Lexibulin complex | x-ray diffraction | F | ACP | 6 (best 0.85) |
| 5CA0 | Crystal structure of T2R-ttl-lexibulin complex | x-ray diffraction | F | — | — |
| 5CA1 | Crystal structure of T2R-ttl-nocodazole complex | x-ray diffraction | F | — | — |
| 5CB4 | Crystal structure of T2R-TTL-Tivantinib complex | x-ray diffraction | F | ACP | 6 (best 0.84) |
| 5CB4 | Crystal structure of T2R-ttl-tivantinib complex | x-ray diffraction | F | — | — |
| 5EZY | Crystal structure of T2R-TTL-taccalonolide AJ complex | x-ray diffraction | F | ACP | 6 (best 0.81) |
| 5EZY | Crystal structure of T2R-ttl-taccalonolide aj complex | x-ray diffraction | F | — | — |
| 5FNV | a new complex structure of tubulin with an alpha-beta unsaturated lactone | x-ray diffraction | F | ACP | 5 (best 0.83) |
| 5FNV | A new complex structure of tubulin with an alpha-beta unsaturated lactone | x-ray diffraction | F | — | — |
| 5GON | Structures of a beta-lactam bridged analogue in complex with tubulin | x-ray diffraction | F | MG | 5 (best 0.88) |
| 5GON | Structures of a beta-lactam bridged analogue in complex with tubulin | x-ray diffraction | F | — | — |
| 5H74 | Crystal structure of T2R-TTL-14b complex | x-ray diffraction | F | ACP | 6 (best 0.80) |
| 5H74 | Crystal structure of T2R-ttl-14B complex | x-ray diffraction | F | — | — |
| 5H7O | Crystal structure of DJ-101 in complex with tubulin protein | x-ray diffraction | F | ACP | 4 (best 0.82) |
| 5H7O | Crystal structure of dj-101 in complex with tubulin protein | x-ray diffraction | F | — | — |
| 5IYZ | Tubulin-MMAE complex | x-ray diffraction | F | MG, ACP | 5 (best 0.81) |
| 5IYZ | Tubulin-mmae complex | x-ray diffraction | F | — | — |
| 5J2T | Tubulin-vinblastine complex | x-ray diffraction | F | — | 5 (best 0.81) |
381 records more on the page itself.
Ligands
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