MolNFT v1 · #178918 · protein + DNA
Orc-DNA: human origin recognition complex (orc) with DNA bound in the core
7JPS: “Orc-DNA: human origin recognition complex (orc) with DNA bound in the core”. Electron microscopy, 3 ligands (ATP, MG, K). MolNFT v1 #178918 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7JPS
- Type
- protein + DNA
- Length
- 1,958 residues
- Chains
- 7
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q13415, Q13416, Q9UBD5, O43929, O43913
- Ligands
- ATP, MG, K
Structure
electron microscopy · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 351 | — | Q13415 |
| B | — | protein | 199 | — | Q13416 |
| C | — | protein | 591 | — | Q9UBD5 |
| D | — | protein | 405 | — | O43929 |
| E | — | protein | 386 | — | O43913 |
| F | — | dna | 13 | — | — |
| G | — | dna | 13 | — | — |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · 3 copies · chains A, D, E
- MG · Magnesium ion · metal · 3 copies · chains A, D, E
- K · Potassium ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7JPS · ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core · the same entry in another collection · chain C against C, TM-score 1.00
- Q13415 · AlphaFold monomer V2.0 prediction for origin recognition complex subunit 1 (Q13415) · a predicted model of the same protein · chain A against A, TM-score 0.98
- Q9UBD5 · AlphaFold monomer V2.0 prediction for origin recognition complex subunit 3 (Q9UBD5) · a predicted model of the same protein · chain C against A, TM-score 0.98
- Q13416 · AlphaFold monomer V2.0 prediction for origin recognition complex subunit 2 (Q13416) · a predicted model of the same protein · chain B against A, TM-score 0.96
- O43929 · AlphaFold monomer V2.0 prediction for origin recognition complex subunit 4 (O43929) · a predicted model of the same protein · chain D against A, TM-score 0.93
- O43913 · AlphaFold monomer V2.0 prediction for origin recognition complex subunit 5 (O43913) · a predicted model of the same protein · chain E against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13415
- Every structure of UniProt Q13416
- Every structure of UniProt Q9UBD5
- Every structure of UniProt O43929
- Every structure of UniProt O43913
- Elsewhere: RCSB PDB 7JPS · PDBe 7JPS · UniProt Q13415 · UniProt Q13416 · UniProt Q9UBD5 · UniProt O43929 · UniProt O43913
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