MolNFT v1 · #282542 · protein
AlphaFold monomer V2.0 prediction for origin recognition complex subunit 4 (O43929)
O43929: “AlphaFold monomer V2.0 prediction for origin recognition complex subunit 4 (O43929)”. 3 pockets (best druggability 0.67). MolNFT v1 #282542 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O43929
- Type
- protein
- Length
- 436 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x99b776DEB2a7E235736ca77F71997f7A305AC803
- Molecule
- Origin recognition complex subunit 4
- UniProt
- O43929
- Pockets
- 3 · best druggability 0.67
Structure
1 distinct chain · 57% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Origin recognition complex subunit 4 | protein | 436 | 57% helix, 8% strand | O43929 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 173 | 0.67 | 0.87 | 32 | empty |
| 2 | 83 | 0.35 | 0.75 | 13 | empty |
| 3 | 67 | 0.30 | 0.74 | 12 | empty |
Compared structures
- 7JPR · ORC-OPEN: Human Origin Recognition Complex (ORC) in an open conformation · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7JPR · Orc-open: human origin recognition complex (orc) in an open conformation · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7JPO · ORC-O1AAA: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC2 WH · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7JPO · Orc-O1AAA: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC2 wh · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7JPP · ORC-O2WH: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC1 AAA+ domain · an experimental structure of the same protein · chain A against D, TM-score 0.87
- 7JPP · Orc-O2WH: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC1 aaa+ domain · an experimental structure of the same protein · chain A against D, TM-score 0.87
- 7JPS · Orc-DNA: human origin recognition complex (orc) with DNA bound in the core · an experimental structure of the same protein · chain A against D, TM-score 0.87
- 7JPS · ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core · an experimental structure of the same protein · chain A against D, TM-score 0.87
- 7CTF · Human origin recognition complex 1-5 State II · an experimental structure of the same protein · chain A against D, TM-score 0.87
- 7CTF · Human origin recognition complex 1-5 state II · an experimental structure of the same protein · chain A against D, TM-score 0.87
- 7CTG · Human origin recognition complex, ORC1-5 state I · an experimental structure of the same protein · chain A against D, TM-score 0.86
- 7CTG · Human Origin Recognition Complex, ORC1-5 State I · an experimental structure of the same protein · chain A against D, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43929
- Elsewhere: UniProt O43929 · AlphaFold DB O43929
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