UniProt Q9UBD5
Origin recognition complex subunit 3 (Q9UBD5)
Origin recognition complex subunit 3 (UniProt Q9UBD5): 19 experimental structures and 1 predicted model on GenesisL1, 78 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UBD5
- Protein
- Origin recognition complex subunit 3
- Experimental structures
- 19
- Predicted models
- 1
- Pockets
- 78 · 9 records with a druggable one
Structures
20 records of Q9UBD5 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UJ8 | Human Origin Recognition Complex subunits 2 and 3 | x-ray diffraction | A, B, C, D | — | — |
| 5UJ8 | Human origin recognition complex subunits 2 and 3 | x-ray diffraction | A, B, C, D | — | — |
| 5UJM | Structure of the active form of human Origin Recognition Complex and its ATPase motor module | electron microscopy | C | — | 10 (best 0.81) |
| 5UJM | Structure of the active form of human origin recognition complex and its ATPase motor module | electron microscopy | C | — | — |
| 7CTE | Human origin recognition complex, ORC2-5 | electron microscopy | C | — | — |
| 7CTF | Human origin recognition complex 1-5 state II | electron microscopy | C | — | — |
| 7CTG | Human Origin Recognition Complex, ORC1-5 State I | electron microscopy | C | — | 12 (best 0.82) |
| 7CTG | Human origin recognition complex, ORC1-5 state I | electron microscopy | C | — | — |
| 7JPO | ORC-O1AAA: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC2 WH | electron microscopy | C | — | 13 (best 0.82) |
| 7JPO | Orc-O1AAA: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC2 wh | electron microscopy | C | — | — |
| 7JPP | Orc-O2WH: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC1 aaa+ domain | electron microscopy | C | — | — |
| 7JPQ | Orc-O2-5: human origin recognition complex (orc) with subunits 2,3,4,5 | electron microscopy | C | — | — |
| 7JPR | Orc-open: human origin recognition complex (orc) in an open conformation | electron microscopy | C | — | — |
| 7JPS | ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core | electron microscopy | C | — | 11 (best 0.84) |
| 7JPS | Orc-DNA: human origin recognition complex (orc) with DNA bound in the core | electron microscopy | C | — | — |
| 8S0C | H. sapiens ORC1-5 bound to double stranded DNA as part of the MCM-ORC complex | electron microscopy | C | — | 14 (best 0.83) |
| 8S0D | H. sapiens MCM bound to double stranded DNA and ORC1-6 | electron microscopy | C | — | 2 (best 0.83) |
| 8S0E | H. sapiens OCCM bound to double stranded DNA | electron microscopy | C | — | 3 (best 0.85) |
| 8S0F | H. sapiens OC1M bound to double stranded DNA | electron microscopy | C | — | 6 (best 0.84) |
| Q9UBD5 | AlphaFold monomer V2.0 prediction for origin recognition complex subunit 3 (Q9UBD5) | predicted | A | — | 7 (best 0.63) |
Experiment against prediction
- 7JPO chain C against the predicted model Q9UBD5: TM-score 0.98, RMSD 1.20 Å
- 7JPO chain C against the predicted model Q9UBD5: TM-score 0.98, RMSD 1.20 Å
- 7JPP chain C against the predicted model Q9UBD5: TM-score 0.98, RMSD 1.23 Å
- 7JPQ chain C against the predicted model Q9UBD5: TM-score 0.98, RMSD 1.23 Å
- 7JPS chain C against the predicted model Q9UBD5: TM-score 0.98, RMSD 1.36 Å
- 7JPS chain C against the predicted model Q9UBD5: TM-score 0.98, RMSD 1.36 Å
- 8S0E chain C against the predicted model Q9UBD5: TM-score 0.98, RMSD 1.34 Å
- 8S0F chain C against the predicted model Q9UBD5: TM-score 0.97, RMSD 1.36 Å
- 7CTF chain C against the predicted model Q9UBD5: TM-score 0.96, RMSD 1.75 Å
- 7CTE chain C against the predicted model Q9UBD5: TM-score 0.96, RMSD 1.76 Å
Elsewhere
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