MolNFT v1 · #282531 · protein
AlphaFold monomer V2.0 prediction for origin recognition complex subunit 3 (Q9UBD5)
Q9UBD5: “AlphaFold monomer V2.0 prediction for origin recognition complex subunit 3 (Q9UBD5)”. 7 pockets (best druggability 0.63). MolNFT v1 #282531 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UBD5
- Type
- protein
- Length
- 711 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x05D249E48b5e19C17E7AE90Ad57354470160c428
- Molecule
- Origin recognition complex subunit 3
- UniProt
- Q9UBD5
- Pockets
- 7 · best druggability 0.63
Structure
1 distinct chain · 61% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Origin recognition complex subunit 3 | protein | 711 | 61% helix, 6% strand | Q9UBD5 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.63 | 0.93 | 20 | empty |
| 2 | 118 | 0.63 | 0.87 | 23 | empty |
| 3 | 249 | 0.60 | 0.79 | 34 | empty |
| 4 | 90 | 0.47 | 0.81 | 18 | empty |
| 5 | 51 | 0.36 | 0.80 | 14 | empty |
Compared structures
- 7JPP · Orc-O2WH: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC1 aaa+ domain · an experimental structure of the same protein · chain A against C, TM-score 0.83
- 7JPO · Orc-O1AAA: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC2 wh · an experimental structure of the same protein · chain A against C, TM-score 0.82
- 7JPS · Orc-DNA: human origin recognition complex (orc) with DNA bound in the core · an experimental structure of the same protein · chain A against C, TM-score 0.81
- 7JPQ · Orc-O2-5: human origin recognition complex (orc) with subunits 2,3,4,5 · an experimental structure of the same protein · chain A against C, TM-score 0.81
- 7CTF · Human origin recognition complex 1-5 state II · an experimental structure of the same protein · chain A against C, TM-score 0.80
- 7CTE · Human origin recognition complex, ORC2-5 · an experimental structure of the same protein · chain A against C, TM-score 0.80
- 7CTG · Human origin recognition complex, ORC1-5 state I · an experimental structure of the same protein · chain A against C, TM-score 0.80
- 7JPR · Orc-open: human origin recognition complex (orc) in an open conformation · an experimental structure of the same protein · chain A against C, TM-score 0.75
- 5UJM · Structure of the active form of human origin recognition complex and its ATPase motor… · an experimental structure of the same protein · chain A against C, TM-score 0.73
- 5UJ8 · Human origin recognition complex subunits 2 and 3 · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 5UJ8 · Human Origin Recognition Complex subunits 2 and 3 · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 8S0D · H. sapiens MCM bound to double stranded DNA and ORC1-6 · an experimental structure of the same protein · chain A against C, TM-score 0.69
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UBD5
- Elsewhere: UniProt Q9UBD5 · AlphaFold DB Q9UBD5
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