MolNFT v1 · #282507 · protein
AlphaFold monomer V2.0 prediction for origin recognition complex subunit 1 (Q13415)
Q13415: “AlphaFold monomer V2.0 prediction for origin recognition complex subunit 1 (Q13415)”. 4 pockets (best druggability 0.60). MolNFT v1 #282507 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q13415
- Type
- protein
- Length
- 861 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xFB04A69429e1aDF578Ed1736131a87ebE5d837bf
- Molecule
- Origin recognition complex subunit 1
- UniProt
- Q13415
- Pockets
- 4 · best druggability 0.60
Structure
1 distinct chain · 28% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Origin recognition complex subunit 1 | protein | 861 | 28% helix, 14% strand | Q13415 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 185 | 0.60 | 0.82 | 30 | empty |
| 2 | 161 | 0.41 | 0.73 | 21 | empty |
| 3 | 67 | 0.32 | 0.74 | 12 | empty |
| 4 | 66 | 0.29 | 0.74 | 16 | empty |
Compared structures
- 7JPO · Orc-O1AAA: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC2 wh · an experimental structure of the same protein · chain A against A, TM-score 0.40
- 7JPR · Orc-open: human origin recognition complex (orc) in an open conformation · an experimental structure of the same protein · chain A against A, TM-score 0.40
- 7JPS · Orc-DNA: human origin recognition complex (orc) with DNA bound in the core · an experimental structure of the same protein · chain A against A, TM-score 0.40
- 5UJ7 · Structure of the active form of human origin recognition complex ATPase motor module… · an experimental structure of the same protein · chain A against A, TM-score 0.39
- 5UJM · Structure of the active form of human origin recognition complex and its ATPase motor… · an experimental structure of the same protein · chain A against A, TM-score 0.39
- 7CTF · Human origin recognition complex 1-5 state II · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 7CTG · Human origin recognition complex, ORC1-5 state I · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 7JPP · Orc-O2WH: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC1 aaa+ domain · an experimental structure of the same protein · chain A against A, TM-score 0.12
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13415
- Elsewhere: UniProt Q13415 · AlphaFold DB Q13415
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