UniProt Q13415
Origin recognition complex subunit 1 (Q13415)
Origin recognition complex subunit 1 (UniProt Q13415): 17 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 61 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13415
- Protein
- Origin recognition complex subunit 1
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 61 · 10 records with a druggable one
Structures
18 records of Q13415 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UJ7 | Structure of the active form of human Origin Recognition Complex ATPase motor module, complex… | x-ray diffraction | A, B | ATP, MG | 12 (best 0.88) |
| 5UJ7 | Structure of the active form of human origin recognition complex ATPase motor module, complex… | x-ray diffraction | A, B | ATP, MG | — |
| 5UJM | Structure of the active form of human Origin Recognition Complex and its ATPase motor module | electron microscopy | A | ATP, MG | 9 (best 0.86) |
| 5UJM | Structure of the active form of human origin recognition complex and its ATPase motor module | electron microscopy | A | ATP, MG | — |
| 7CTF | Human origin recognition complex 1-5 state II | electron microscopy | A | — | — |
| 7CTG | Human Origin Recognition Complex, ORC1-5 State I | electron microscopy | A | — | 5 (best 0.82) |
| 7CTG | Human origin recognition complex, ORC1-5 state I | electron microscopy | A | — | — |
| 7JPO | ORC-O1AAA: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC2 WH | electron microscopy | A | ATP, MG | 7 (best 0.84) |
| 7JPO | Orc-O1AAA: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC2 wh | electron microscopy | A | ATP, MG | — |
| 7JPP | Orc-O2WH: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC1 aaa+ domain | electron microscopy | A | — | — |
| 7JPR | Orc-open: human origin recognition complex (orc) in an open conformation | electron microscopy | A | ATP, MG | — |
| 7JPS | ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core | electron microscopy | A | ATP, MG | 9 (best 0.84) |
| 7JPS | Orc-DNA: human origin recognition complex (orc) with DNA bound in the core | electron microscopy | A | ATP, MG | — |
| 8S0C | H. sapiens ORC1-5 bound to double stranded DNA as part of the MCM-ORC complex | electron microscopy | A | — | 3 (best 0.86) |
| 8S0D | H. sapiens MCM bound to double stranded DNA and ORC1-6 | electron microscopy | A | — | 1 (best 0.86) |
| 8S0E | H. sapiens OCCM bound to double stranded DNA | electron microscopy | A | AGS, MG | 7 (best 0.89) |
| 8S0F | H. sapiens OC1M bound to double stranded DNA | electron microscopy | A | AGS, MG | 4 (best 0.86) |
| Q13415 | AlphaFold monomer V2.0 prediction for origin recognition complex subunit 1 (Q13415) | predicted | A | — | 4 (best 0.60) |
Ligands
Experiment against prediction
- 7CTF chain A against the predicted model Q13415: TM-score 0.99, RMSD 0.44 Å
- 7CTG chain A against the predicted model Q13415: TM-score 0.99, RMSD 0.45 Å
- 7CTG chain A against the predicted model Q13415: TM-score 0.99, RMSD 0.45 Å
- 5UJ7 chain B against the predicted model Q13415: TM-score 0.98, RMSD 0.94 Å
- 5UJ7 chain A against the predicted model Q13415: TM-score 0.98, RMSD 0.95 Å
- 5UJ7 chain A against the predicted model Q13415: TM-score 0.98, RMSD 0.95 Å
- 5UJM chain A against the predicted model Q13415: TM-score 0.98, RMSD 0.95 Å
- 5UJM chain A against the predicted model Q13415: TM-score 0.98, RMSD 0.95 Å
- 7JPO chain A against the predicted model Q13415: TM-score 0.98, RMSD 1.03 Å
- 7JPO chain A against the predicted model Q13415: TM-score 0.98, RMSD 1.03 Å
Elsewhere
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