MolNFT v1 · #173733 · protein
Structure of a minimal SF3B core in complex with spliceostatin a (form I)
7B9C: “Structure of a minimal SF3B core in complex with spliceostatin a (form I)”. X-ray diffraction, 3 ligands (SJT, ZN, SCN). MolNFT v1 #173733 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7B9C
- Type
- protein
- Length
- 1,878 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q921M3, Q15393, Q9BWJ5, O75533, Q7RTV0
- Ligands
- SJT, ZN, SCN
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 870 | — | Q921M3, Q15393 |
| B | — | protein | 74 | — | Q9BWJ5 |
| C | — | protein | 842 | — | O75533 |
| D | — | protein | 92 | — | Q7RTV0 |
Ligands and binding sites
- SJT · spliceostatin A (form II) · ligand · chains C, D
- ZN · Zinc ion · metal · 3 copies · chains D
- SCN · Thiocyanate ion · ion · chains D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7B9C · Structure of a minimal SF3B core in complex with spliceostatin A (form I) · the same entry in another collection · chain A against A, TM-score 1.00
- Q15393 · AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 3 (Q15393) · a predicted model of the same protein · chain A against A, TM-score 0.99
- Q921M3 · AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 3 (Q921M3) · a predicted model of the same protein · chain A against A, TM-score 0.99
- Q7RTV0 · AlphaFold monomer V2.0 prediction for phd finger-like domain- containing protein 5A… · a predicted model of the same protein · chain D against A, TM-score 0.89
- Q9BWJ5 · AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 5 (Q9BWJ5) · a predicted model of the same protein · chain B against A, TM-score 0.88
- O75533 · AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 1 (O75533) · a predicted model of the same protein · chain C against A, TM-score 0.80
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q921M3
- Every structure of UniProt Q15393
- Every structure of UniProt Q9BWJ5
- Every structure of UniProt O75533
- Every structure of UniProt Q7RTV0
- Elsewhere: RCSB PDB 7B9C · PDBe 7B9C · UniProt Q921M3 · UniProt Q15393 · UniProt Q9BWJ5 · UniProt O75533 · UniProt Q7RTV0
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