GL1X · GenesisL1 explorer

Ligand · SJT

SJT · spliceostatin A (form II)

SJT, spliceostatin A (form II) (C28 H45 N O8, 523.7 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
SJT
Formula
C28 H45 N O8
Class
ligand
Structures
5
PDB entries
4

Binding sites

SJT in 5 structures; the first of them:

  • 7B0I · Structure of a minimal SF3B core in complex with spliceostatin A (form II) · SJT D1401 · binds LEU1066, LYS1067, HIS1069, ARG1074, ARG1075, VAL1110, CYS1111, VAL1114 and 5 more
  • 7VPX · The cryo-EM structure of the human pre-A complex · SJT 6204 · binds LEU1066, LYS1067, ARG1074, VAL1078, GLN1107, VAL1114, PHE1153, TYR1157 and 4 more
  • 7B0I · Structure of a minimal SF3B core in complex with spliceostatin a (form II) · SJT D1401 · binds LEU1066, LYS1067, HIS1069, ARG1074, ARG1075, VAL1110, CYS1111, VAL1114 and 5 more
  • 7B9C · Structure of a minimal SF3B core in complex with spliceostatin a (form I) · SJT D105 · binds LEU1066, LYS1067, ALA1068, HIS1069, ARG1074, ARG1075, VAL1078, VAL1110 and 8 more
  • 7ONB · Structure of the U2 5' module of the A3'-ssa complex · SJT D1401 · binds LEU1066, LYS1067, ALA1068, ARG1074, VAL1078, CYS1111, VAL1114, PHE1153 and 5 more

Residues it binds most

LYS 5, VAL 5, CYS 5, ARG 5, TYR 5, LEU 5, HIS 3, ILE 3, PHE 3, ALA 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • SCN · Thiocyanate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.