UniProt Q02MM2
CRISPR-associated endonuclease Cas6/Csy4 (Q02MM2)
CRISPR-associated endonuclease Cas6/Csy4 (UniProt Q02MM2), EC 3.1.-.-: 23 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02MM2
- Protein
- CRISPR-associated endonuclease Cas6/Csy4
- EC
- 3.1.-.-
- Experimental structures
- 23
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
24 records of Q02MM2 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4AL5 | Crystal structure of the Csy4-crRNA product complex | x-ray diffraction | A | — | — |
| 4AL5 | Crystal structure of the CSY4-crrna product complex | x-ray diffraction | A | — | — |
| 4AL6 | Crystal structure of the S148ACsy4-crRNA complex | x-ray diffraction | A | — | — |
| 4AL6 | Crystal structure of the S148ACSY4-crrna complex | x-ray diffraction | A | — | — |
| 4AL7 | Crystal structure of the Csy4-minimal crRNA complex | x-ray diffraction | A | — | — |
| 4AL7 | Crystal structure of the CSY4-minimal crrna complex | x-ray diffraction | A | — | — |
| 5UZ9 | Cryo EM structure of anti-crisprs, ACRF1 and ACRF2, bound to type I-F crrna-guided CRISPR… | electron microscopy | L | — | — |
| 6B44 | Cryo-EM structure of type I-F CRISPR crrna-guided csy surveillance complex with bound target dsdna | electron microscopy | L | — | — |
| 6B45 | Cryo-EM structure of type I-F CRISPR crrna-guided csy surveillance complex | electron microscopy | L | — | — |
| 6B46 | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR… | electron microscopy | L | — | — |
| 6B46 | Cryo-EM structure of type I-F CRISPR crrna-guided csy surveillance complex with bound anti-CRISPR… | electron microscopy | L | — | — |
| 6B47 | Cryo-EM structure of type I-F CRISPR crrna-guided csy surveillance complex with bound anti-CRISPR… | electron microscopy | L | — | — |
| 6B48 | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR… | electron microscopy | L | — | 2 (best 0.74) |
| 6B48 | Cryo-EM structure of type I-F CRISPR crrna-guided csy surveillance complex with bound anti-CRISPR… | electron microscopy | L | — | — |
| 6NE0 | Structure of double-stranded target DNA engaged csy complex from pseudomonas aeruginosa (pa-14) | electron microscopy | L | — | — |
| 6VQV | Type I-F CRISPR-csy complex with its inhibitor ACRF9 | electron microscopy | K | — | — |
| 6VQW | Type I-F CRISPR-csy complex with its inhibitor ACRF8 | electron microscopy | J | — | — |
| 6VQX | Type I-F CRISPR-csy complex with its inhibitor ACRF6 | electron microscopy | J | — | — |
| 6W1X | Cryo-EM structure of anti-CRISPR ACRIF9, bound to the type I-F crrna- guided CRISPR surveillance… | electron microscopy | L | — | — |
| 6WHI | Cryo-electron microscopy structure of the type I-F CRISPR RNA-guided surveillance complex bound to… | electron microscopy | L | — | — |
| 7JZW | Cryo-EM structure of CRISPR-Cas surveillance complex with AcrIF4 | electron microscopy | C | — | — |
| 7JZW | Cryo-EM structure of CRISPR-CAS surveillance complex with ACRIF4 | electron microscopy | C | — | — |
| 7JZX | Cryo-EM structure of CRISPR-CAS surveillance complex with ACRIF7 | electron microscopy | C | — | — |
| Q02MM2 | AlphaFold monomer V2.0 prediction for CRISPR-associated endonuclease CAS6/CSY4 (Q02MM2) | predicted | A | — | — |
Experiment against prediction
- 7JZW chain C against the predicted model Q02MM2: TM-score 0.98, RMSD 0.69 Å
- 7JZW chain C against the predicted model Q02MM2: TM-score 0.98, RMSD 0.69 Å
- 7JZX chain C against the predicted model Q02MM2: TM-score 0.98, RMSD 0.73 Å
- 4AL5 chain A against the predicted model Q02MM2: TM-score 0.97, RMSD 0.83 Å
- 4AL5 chain A against the predicted model Q02MM2: TM-score 0.97, RMSD 0.83 Å
- 4AL6 chain A against the predicted model Q02MM2: TM-score 0.97, RMSD 0.56 Å
- 4AL6 chain A against the predicted model Q02MM2: TM-score 0.97, RMSD 0.56 Å
- 4AL7 chain A against the predicted model Q02MM2: TM-score 0.97, RMSD 0.59 Å
- 4AL7 chain A against the predicted model Q02MM2: TM-score 0.97, RMSD 0.59 Å
- 6WHI chain L against the predicted model Q02MM2: TM-score 0.89, RMSD 1.87 Å
Elsewhere
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