UniProt P22897
Macrophage mannose receptor 1 (P22897)
Macrophage mannose receptor 1 (UniProt P22897): 37 experimental structures and 1 predicted model on GenesisL1, 8 ligands bound, 43 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P22897
- Protein
- Macrophage mannose receptor 1
- Experimental structures
- 37
- Predicted models
- 1
- Ligands
- 8
- Pockets
- 43 · 3 records with a druggable one
Structures
38 records of P22897 in the MolNFT archive: 37 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EGG | Structure of a C-type carbohydrate-recognition domain (crd-4) from the macrophage mannose receptor | x-ray diffraction | A, B | — | — |
| 1EGG | Structure of a C-type carbohydrate-recognition domain (crd- 4) from the macrophage mannose receptor | x-ray diffraction | A, B | — | — |
| 1EGI | Structure of a C-type carbohydrate-recognition domain (crd-4) from the macrophage mannose receptor | x-ray diffraction | A, B | — | — |
| 1EGI | Structure of a C-type carbohydrate-recognition domain (crd- 4) from the macrophage mannose receptor | x-ray diffraction | A, B | — | — |
| 5XTS | Crystal structure of the CysR-CTLD3 fragment of human MR at basic/neutral pH | x-ray diffraction | A | CA | 4 (best 0.39) |
| 5XTS | Crystal structure of the cysr-CTLD3 fragment of human mr at BASIC/NEUTRAL pH | x-ray diffraction | A | CA | — |
| 5XTW | Crystal structure of the CysR-CTLD2 fragment of human MR at acidic pH | x-ray diffraction | A, B, C, D, E, F, G, H | CA | 20 (best 0.74) |
| 5XTW | Crystal structure of the cysr-CTLD2 fragment of human mr at acidic pH | x-ray diffraction | A, B, C, D, E, F, G, H | CA | — |
| 6INN | Crystal structure of the cysr-CTLD3 fragment of human mr at acidic pH (pH 5.6) | x-ray diffraction | A, B, C, D | — | — |
| 6INO | Crystal structure of the cysr-CTLD2 fragment of human mr at acidic pH (pH 4.6) | x-ray diffraction | A, B | — | — |
| 6INU | Crystal structure of the CysR-CTLD2 fragment of human MR at acidic pH (pH 4.6) | x-ray diffraction | A, B | — | — |
| 6INU | Crystal structure of the cysr-CTLD2 fragment of human mr at acidic pH (pH 4.6) | x-ray diffraction | A, B | — | — |
| 6INV | Crystal structure of the CysR-CTLD2 fragment of human MR at acidic pH (pH 4.0) | x-ray diffraction | A | — | — |
| 6INV | Crystal structure of the cysr-CTLD2 fragment of human mr at acidic pH (pH 4.0) | x-ray diffraction | A | — | — |
| 6IOE | Crystal structure of the CysR-CTLD2 fragment of human MR at basic pH (pH 8.5) | x-ray diffraction | A, B | — | — |
| 6IOE | Crystal structure of the cysr-CTLD2 fragment of human mr at basic pH (pH 8.5) | x-ray diffraction | A, B | — | — |
| 7JUB | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with methyl-mannoside | x-ray diffraction | A | CA, MMA | — |
| 7JUB | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with methyl-mannoside | x-ray diffraction | A | CA, MMA | — |
| 7JUC | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with methyl-mannoside | x-ray diffraction | A | CA, MMA | — |
| 7JUD | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with methyl-mannoside | x-ray diffraction | A, B | CA, MMA | 1 (best 0.64) |
| 7JUD | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with methyl-mannoside | x-ray diffraction | A, B | CA, MMA | — |
| 7JUE | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with man-ALPHA1-2MAN | x-ray diffraction | A | MAN, CA | — |
| 7JUF | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with man-ALPHA1-2MAN | x-ray diffraction | A, B | MAN, CA | — |
| 7JUG | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with man-ALPHA1-6MAN | x-ray diffraction | A | CA, MAN | — |
| 7JUH | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with man-ALPHA1-6MAN | x-ray diffraction | A | CA, MAN | — |
| 7L61 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with L-fucose-(alpha… | x-ray diffraction | A | BGC, FUC, CA | — |
| 7L62 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with L-fucose-(alpha… | x-ray diffraction | A | BGC, GAL, FUC, CA | — |
| 7L62 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with L-fucose-(alpha… | x-ray diffraction | A | BGC, GAL, FUC, CA | — |
| 7L63 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with L-fucose-(alpha… | x-ray diffraction | A | BGC, GAL, FUC, CA | — |
| 7L63 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with L-fucose-(alpha… | x-ray diffraction | A | BGC, GAL, FUC, CA | — |
| 7L64 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with lewis-a | x-ray diffraction | A | NAG, GAL, FUC, CA | — |
| 7L65 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with Methyl-GlcNAc | x-ray diffraction | A | CA, 2F8 | — |
| 7L65 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with methyl-glcnac | x-ray diffraction | A | CA, 2F8 | — |
| 7L66 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with methyl-glcnac | x-ray diffraction | A | CA, 2F8 | — |
| 7L67 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with… | x-ray diffraction | A | NAG, FUC, CA | — |
| 7L67 | C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with… | x-ray diffraction | A | NAG, FUC, CA | — |
| 7L68 | C-type carbohydrate-recognition domain 4 of the mannose receptor | x-ray diffraction | A, B | CA | — |
| P22897 | AlphaFold monomer V2.0 prediction for macrophage mannose receptor 1 (P22897) | predicted | A | — | 18 (best 0.82) |
Ligands
- CA · Calcium ion · in 25 records
- FUC · alpha-L-fucopyranose · in 8 records
- BGC · beta-D-glucopyranose · in 5 records
- GAL · beta-D-galactopyranose · in 5 records
- MMA · methyl alpha-D-mannopyranoside · in 5 records
- MAN · alpha-D-mannopyranose · in 4 records
- 2F8 · methyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside · in 3 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 3 records
Experiment against prediction
- 7L64 chain A against the predicted model P22897: TM-score 0.98, RMSD 0.62 Å
- 7L65 chain A against the predicted model P22897: TM-score 0.98, RMSD 0.64 Å
- 7L65 chain A against the predicted model P22897: TM-score 0.98, RMSD 0.64 Å
- 7JUB chain A against the predicted model P22897: TM-score 0.98, RMSD 0.64 Å
- 7JUB chain A against the predicted model P22897: TM-score 0.98, RMSD 0.64 Å
- 7L61 chain A against the predicted model P22897: TM-score 0.98, RMSD 0.66 Å
- 7JUD chain A against the predicted model P22897: TM-score 0.97, RMSD 0.71 Å
- 7JUD chain A against the predicted model P22897: TM-score 0.97, RMSD 0.71 Å
- 7L66 chain A against the predicted model P22897: TM-score 0.97, RMSD 0.75 Å
- 7L63 chain A against the predicted model P22897: TM-score 0.97, RMSD 0.83 Å
Elsewhere
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