MolNFT v1 · #152623 · protein
Crystal structure of the cysr-CTLD2 fragment of human mr at acidic pH (pH 4.0)
6INV · Macrophage mannose receptor 1: “Crystal structure of the cysr-CTLD2 fragment of human mr at acidic pH (pH 4.0)”. X-ray diffraction, 2 pockets (best druggability 0.52). MolNFT v1 #152623 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6INV
- Type
- protein
- Length
- 438 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Macrophage mannose receptor 1
- UniProt
- P22897
- Pockets
- 2 · best druggability 0.52
Structure
x-ray diffraction · 1 distinct chain · 13% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Macrophage mannose receptor 1 | protein | 438 | 13% helix, 32% strand | P22897 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 212 | 0.52 | 0.77 | 35 | empty |
| 2 | 59 | 0.26 | 0.73 | 13 | empty |
Modifications
Observed in the structure: 9 disulfide (disulfide).
Compared structures
- 6INV · Crystal structure of the CysR-CTLD2 fragment of human MR at acidic pH (pH 4.0) · the same entry in another collection · chain A against A, TM-score 1.00
- P22897 · AlphaFold monomer V2.0 prediction for macrophage mannose receptor 1 (P22897) · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22897
- Elsewhere: RCSB PDB 6INV · PDBe 6INV · UniProt P22897
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