UniProt P03300
P1/MAHONEY poliovirus (P03300)
P1/MAHONEY poliovirus (UniProt P03300), EC 2.7.7.48, 3.4.22.28: 146 experimental structures on GenesisL1, 17 ligands bound, 660 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P03300
- Protein
- P1/MAHONEY poliovirus
- EC
- 2.7.7.48, 3.4.22.28, 3.4.22.29, 3.6.1.15
- Experimental structures
- 146
- Predicted models
- 0
- Ligands
- 17
- Pockets
- 660 · 80 records with a druggable one
Structures
146 records of P03300 in the MolNFT archive: 146 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AL2 | P1/MAHONEY poliovirus, single site mutant V1160I | x-ray diffraction | 1, 2, 3 | SPH | 12 (best 0.78) |
| 1AL2 | P1/MAHONEY poliovirus, single site mutant V1160I | x-ray diffraction | 1, 2, 3 | SPH | 12 (best 0.78) |
| 1AR6 | P1/MAHONEY poliovirus, double mutant V1160I +P1095S | x-ray diffraction | 1, 2, 3 | SPH | 12 (best 0.78) |
| 1AR6 | P1/MAHONEY poliovirus, double mutant V1160I +P1095S | x-ray diffraction | 1, 2, 3 | SPH | 10 (best 0.78) |
| 1AR7 | P1/MAHONEY poliovirus, double mutant P1095S + H2142Y | x-ray diffraction | 1, 2, 3 | SPH | 13 (best 0.78) |
| 1AR7 | P1/MAHONEY poliovirus, double mutant P1095S + H2142Y | x-ray diffraction | 1, 2, 3 | SPH | 13 (best 0.79) |
| 1AR8 | P1/MAHONEY poliovirus, mutant P1095S | x-ray diffraction | 1, 2, 3 | SPH | 12 (best 0.79) |
| 1AR8 | P1/MAHONEY poliovirus, mutant P1095S | x-ray diffraction | 1, 2, 3 | SPH | 12 (best 0.79) |
| 1AR9 | P1/MAHONEY poliovirus, single site mutant H2142Y | x-ray diffraction | 1, 2, 3 | SPH | 11 (best 0.78) |
| 1AR9 | P1/MAHONEY poliovirus, single site mutant H2142Y | x-ray diffraction | 1, 2, 3 | SPH | 13 (best 0.78) |
| 1ASJ | P1/MAHONEY poliovirus, at cryogenic temperature | x-ray diffraction | 1, 2, 3 | SPH | 13 (best 0.78) |
| 1ASJ | P1/MAHONEY poliovirus, at cryogenic temperature | x-ray diffraction | 1, 2, 3 | SPH | 12 (best 0.79) |
| 1DGI | Cryo-EM structure of human poliovirus(serotype 1)complexed with three domain CD155 | electron microscopy | 1, 2, 3 | — | 3 (best 0.32) |
| 1DGI | Cryo-EM structure of human POLIOVIRUS(SEROTYPE 1)COMPLEXED with three domain CD155 | electron microscopy | 1, 2, 3 | — | 3 (best 0.32) |
| 1HXS | Crystal structure of mahoney strain of poliovirus at 2.2A resolution | x-ray diffraction | 1, 2, 3, 4 | PLM, MYR | 13 (best 0.78) |
| 1HXS | Crystal structure of mahoney strain of poliovirus at 2.2A resolution | x-ray diffraction | 1, 2, 3, 4 | PLM, MYR | 13 (best 0.77) |
| 1L1N | Poliovirus 3C proteinase | x-ray diffraction | A, B | — | 1 (best 0.28) |
| 1L1N | Poliovirus 3C proteinase | x-ray diffraction | A, B | — | 1 (best 0.28) |
| 1NG7 | The Solution Structure of the Soluble Domain of Poliovirus 3A Protein | solution nmr | A, B | — | 2 (best 0.47) |
| 1NG7 | The solution structure of the soluble domain of poliovirus 3A protein | solution nmr | A, B | — | 2 (best 0.47) |
| 1NN8 | CryoEM structure of poliovirus receptor bound to poliovirus | electron microscopy | 1, 2, 3, 4 | MYR | 1 (best 0.44) |
| 1NN8 | Cryoem structure of poliovirus receptor bound to poliovirus | electron microscopy | 1, 2, 3, 4 | MYR | 1 (best 0.44) |
| 1PO1 | Poliovirus (type 1, mahoney) in complex with R80633, an inhibitor of viral replication | x-ray diffraction | 1, 2, 3 | J80 | 10 (best 0.80) |
| 1PO1 | Poliovirus (type 1, mahoney) in complex with R80633, an inhibitor of viral replication | x-ray diffraction | 1, 2, 3 | J80 | 13 (best 0.80) |
| 1PO2 | Poliovirus (type 1, mahoney) in complex with R77975, an inhibitor of viral replication | x-ray diffraction | 1, 2, 3 | J77 | 13 (best 0.79) |
| 1PO2 | Poliovirus (type 1, mahoney) in complex with R77975, an inhibitor of viral replication | x-ray diffraction | 1, 2, 3 | J77 | 14 (best 0.79) |
| 1POV | Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty… | x-ray diffraction | 0, 1, 3 | MYR, SPH | 11 (best 0.79) |
| 1POV | Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty… | x-ray diffraction | 0, 1, 3 | MYR, SPH | 11 (best 0.80) |
| 1RA6 | Poliovirus Polymerase Full Length Apo Structure | x-ray diffraction | A | — | 3 (best 0.71) |
| 1RA6 | Poliovirus polymerase full length apo structure | x-ray diffraction | A | — | 3 (best 0.71) |
| 1RA7 | Poliovirus Polymerase with GTP | x-ray diffraction | A | GTP | 2 (best 0.69) |
| 1RA7 | Poliovirus polymerase with GTP | x-ray diffraction | A | GTP | 2 (best 0.69) |
| 1RAJ | Poliovirus Polymerase with a 68 residue N-terminal truncation | x-ray diffraction | A | — | 3 (best 0.52) |
| 1RAJ | Poliovirus polymerase with a 68 residue N-terminal truncation | x-ray diffraction | A | — | 3 (best 0.52) |
| 1RDR | Poliovirus 3D polymerase | x-ray diffraction | A | CA | 4 (best 0.49) |
| 1RDR | Poliovirus 3D polymerase | x-ray diffraction | A | CA | 4 (best 0.49) |
| 1TQL | Poliovirus polymerase G1A mutant | x-ray diffraction | A | — | 1 (best 0.71) |
| 1TQL | Poliovirus polymerase G1A mutant | x-ray diffraction | A | — | 1 (best 0.71) |
| 1VBD | Poliovirus (type 1, mahoney strain) complexed with R78206 | x-ray diffraction | 1, 2, 3 | J78 | 14 (best 0.80) |
| 1VBD | Poliovirus (type 1, mahoney strain) complexed with R78206 | x-ray diffraction | 1, 2, 3 | J78 | 11 (best 0.80) |
| 1XYR | Poliovirus 135S cell entry intermediate | electron microscopy | 1, 2, 3, 5, 6, 7, 8 | — | — |
| 1XYR | Poliovirus 135S cell entry intermediate | electron microscopy | 1, 2, 3, 5, 6, 7, 8 | — | — |
| 2BBP | NMR structures of the peptide linked to the genome (VPg) of poliovirus | solution nmr | A | — | — |
| 2BBP | NMR structures of the peptide linked to the genome (vpg) of poliovirus | solution nmr | A | — | — |
| 2IJD | Crystal Structure of the Poliovirus Precursor Protein 3CD | x-ray diffraction | 1, 2 | ZN, SO4 | 6 (best 0.73) |
| 2IJD | Crystal structure of the poliovirus precursor protein 3CD | x-ray diffraction | 1, 2 | ZN, SO4 | 6 (best 0.73) |
| 2IJF | Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Fidelity Mutant 3Dpol G64S | x-ray diffraction | A | — | 2 (best 0.70) |
| 2IJF | Crystal structure of the poliovirus RNA-dependent RNA polymerase fidelity mutant 3DPOL G64S | x-ray diffraction | A | — | 2 (best 0.70) |
| 2ILY | Crystal structure of poliovirus polymerase complexed with ATP and Mg2+ | x-ray diffraction | A | NA, ATP | 5 (best 0.58) |
| 2ILY | Crystal structure of poliovirus polymerase complexed with ATP and MG2+ | x-ray diffraction | A | NA, ATP | 5 (best 0.58) |
| 2ILZ | Crystal structure of poliovirus polymerase complexed with GTP and Mn2+ | x-ray diffraction | A | MN, NA, GTP | 4 (best 0.64) |
| 2ILZ | Crystal structure of poliovirus polymerase complexed with GTP and MN2+ | x-ray diffraction | A | MN, NA, GTP | 4 (best 0.64) |
| 2IM0 | Crystal structure of poliovirus polymerase complexed with CTP and Mg2+ | x-ray diffraction | A | NA, CTP | 3 (best 0.71) |
| 2IM0 | Crystal structure of poliovirus polymerase complexed with CTP and MG2+ | x-ray diffraction | A | NA, CTP | 3 (best 0.71) |
| 2IM1 | Crystal structure of poliovirus polymerase complexed with CTP and Mn2+ | x-ray diffraction | A | MN, NA, CTP | 4 (best 0.70) |
| 2IM1 | Crystal structure of poliovirus polymerase complexed with CTP and MN2+ | x-ray diffraction | A | MN, NA, CTP | 4 (best 0.70) |
| 2IM2 | Crystal structure of poliovirus polymerase complexed with UTP and Mg2+ | x-ray diffraction | A | NA, UTP | 4 (best 0.67) |
| 2IM2 | Crystal structure of poliovirus polymerase complexed with UTP and MG2+ | x-ray diffraction | A | NA, UTP | 4 (best 0.67) |
| 2IM3 | Crystal structure of poliovirus polymerase complexed with UTP and Mn2+ | x-ray diffraction | A | MN, NA, UTP | 4 (best 0.65) |
| 2IM3 | Crystal structure of poliovirus polymerase complexed with UTP and MN2+ | x-ray diffraction | A | MN, NA, UTP | 4 (best 0.65) |
86 records more on the page itself.
Ligands
- NA · Sodium ion · in 23 records
- SPH · Sphingosine · in 18 records
- MYR · Myristic acid · in 11 records
- PLM · Palmitic acid · in 8 records
- MN · Manganese (II) ion · in 6 records
- ZN · Zinc ion · in 6 records
- SO4 · Sulfate ion · in 5 records
- CTP · Cytidine-5'-triphosphate · in 4 records
- GTP · Guanosine-5'-triphosphate · in 4 records
- UTP · Uridine 5'-triphosphate · in 4 records
- ATP · Adenosine-5'-triphosphate · in 2 records
- CA · Calcium ion · in 2 records
- J77 · (methylpyridazine piperidine ethyloxyphenyl)ethylacetate · in 2 records
- J78 · (methylpyridazine piperidine propyloxyphenyl)ethylacetate · in 2 records
- J80 · (methylpyridazine piperidine butyloxyphenyl)ethylacetate · in 2 records
- PO4 · Phosphate ion · in 2 records
- K36 · (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid · in 1 record
Elsewhere
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