GL1X · GenesisL1 explorer

Ligand · CTP

CTP · Cytidine-5'-triphosphate

CTP, Cytidine-5'-triphosphate (C9 H16 N3 O14 P3, 483.2 g/mol), in the MolNFT structures on GenesisL1: bound in 87 records (69 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
CTP
Formula
C9 H16 N3 O14 P3
Class
ligand
Structures
87
PDB entries
69

Binding sites

CTP in 87 structures; the first of them:

  • 5A2X · Crystal structure of mtPAP in complex with CTP · CTP A1528 · binds PHE224, GLY225, SER226, ASN229, ASP239, ALA327, CYS330, SER331 and 4 more
  • 5BO7 · Structure of human sialyltransferase ST8SiaIII in complex with CTP · CTP A410 · binds GLY166, ASN167, SER168, CYS189, ASN190, SER300, THR301, GLY302 and 11 more
  • 5EOM · Structure of full-length human MAB21L1 with bound CTP · CTP A403 · binds ARG23, LYS24, ILE27, ALA28, ILE31, ARG62, TYR63, LEU66 and 4 more
  • 5EWE · Ternary complex of human DNA polymerase eta inserting rCTP opposite template G · CTP A501 · binds ASP13, MET14, ASP15, CYS16, PHE17, PHE18, ILE48, ALA49 and 10 more
  • 5EXY · Crystal structure of in cellulo recombinant CPV1 Polyhedra · CTP A306 · binds HIS76, ASN77, ASP78, SER79, TYR80, ASP81, ASP96, ARG98
  • 5EXZ · Crystal structure of purified recombinant CPV1 Polyhedra · CTP A306 · binds HIS76, ASN77, ASP78, SER79, TYR80, ASP81, ASP96, ALA97 and 1 more
  • 5F8I · Enterovirus 71 Polymerase Elongation Complex (C1S2/3 Form) · CTP A1001 · binds LYS159, ARG163, ARG174, TYR234, GLY236, TYR237, ASP238, SER289 and 5 more
  • 5GQI · Crystal structure of Cypovirus Polyhedra mutant with deletion of Ala194 · CTP A306 · binds HIS76, ASN77, ASP78, SER79, TYR80, ASP81, GLU84, ASP96 and 2 more
  • 5GQJ · Crystal structure of Cypovirus Polyhedra mutant with deletion of Ser193 and Ala194 · CTP A305 · binds HIS76, ASN77, ASP78, SER79, TYR80, ASP81, GLU84, ASP96 and 2 more
  • 5GQL · Crystal structure of Wild Type Cypovirus Polyhedra · CTP A304 · binds HIS76, ASN77, ASP78, SER79, TYR80, ASP81, GLU84, ASP96 and 2 more
  • 5GQM · Crystal structure of in cellulo Wild Type Cypovirus Polyhedra · CTP A306 · binds HIS76, ASN77, ASP78, SER79, TYR80, ASP81, GLU84, ASP96 and 2 more
  • 5GUF · Structural insight into an intramembrane enzyme for archaeal membrane lipids biosynthesis · CTP A201 · binds PRO31, VAL32, GLY35, LEU53, GLY56, LYS57, THR58, GLY61 and 10 more
  • 5HS2 · Crystal structure of IspD complexed with CTP and Mg2+ from Bacillus subtilis at 1.90… · CTP A301 · binds PRO8, ALA9, ALA10, GLY11, GLN12, GLY13, LYS14, ARG15 and 11 more
  • 5TKV · X-ray crystal structure of the closed" conformation of CTP-inhibited E. COLI cytidine… · CTP B601 · binds SER14, THR144, ASP147, ILE148, GLU149, VAL186, LYS187, THR188 and 4 more
  • 5TRD · Structure of RbkR (Riboflavin Kinase) from Thermoplasma acidophilum determined in complex… · CTP A301 · binds SER101, GLY102, MET103, GLY104, GLU105, GLY106, ARG107, TYR128 and 9 more
  • 5U3C · CryoEM structure of the CTP synthase filament at 4.6 Angstrom resolution · CTP A601 · binds SER14, ASP147, ILE148, GLU149, GLN114, VAL115, ILE116, THR188 and 3 more
  • 5U6R · E. coli CTP synthase CC mutant filament (product-bound) · CTP A601 · binds SER14, ASP147, ILE148, GLU149, GLN114, VAL115, ILE116, THR188 and 3 more
  • 6CKK · N. meningitidis CMP-sialic acid synthetase in the presence of CTP and Ca2+ · CTP A701 · binds LEU10, ALA11, ARG12, SER15, LYS16, GLY17, LEU18, LYS21 and 11 more
  • 6E05 · Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with… · CTP A302 · binds GLY10, THR11, GLY12, VAL13, GLY14, LYS15, THR16, VAL17 and 12 more

Residues it binds most

LYS 279, ASP 268, GLY 167, ILE 209, VAL 219, SER 245, GLU 214, ALA 112, ARG 110, GLN 125 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • CA · Calcium ion
  • GOL · Glycerol
  • CL · Chloride ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • ACT · Acetate ion
  • ATP · Adenosine-5'-triphosphate
  • EDO · 1,2-ethanediol
  • ADP · Adenosine-5'-diphosphate
  • MN · Manganese (II) ion
  • PO4 · Phosphate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.