MolNFT v1 · #13115 · protein
Poliovirus 3C proteinase
1L1N · Genome polyprotein: picornain 3C: “Poliovirus 3C proteinase”. X-ray diffraction, 1 pocket (best druggability 0.28). MolNFT v1 #13115 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1L1N
- Type
- protein
- Length
- 358 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Genome polyprotein: picornain 3C
- EC
- 3.4.22.28
- UniProt
- P03300
- Pockets
- 1 · best druggability 0.28
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 56% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Genome polyprotein: picornain 3C (EC 3.4.22.28) | protein | 180 | 11% helix, 56% strand | P03300 |
| B | Genome polyprotein: picornain 3C (EC 3.4.22.28) | protein | 178 | 12% helix, 56% strand | P03300 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.28 | 0.74 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 705 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 1L1N · Poliovirus 3C proteinase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03300
- Elsewhere: RCSB PDB 1L1N · PDBe 1L1N · UniProt P03300
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