MolNFT v2 · #196511 · protein + DNA
Complex between MLL1-WRAD and an H2B-ubiquitinated nucleosome
7UD5: “Complex between MLL1-WRAD and an H2B-ubiquitinated nucleosome”. Electron microscopy at 4.25, 1 ligand (ZN). MolNFT v2 #196511 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7UD5
- Type
- protein + DNA
- Length
- 2,398 residues
- Chains
- 17
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 4.25
- Source
- Homo sapiens; synthetic construct; Xenopus laevis
- UniProt
- A0A310TTQ1, P62799, Q6AZJ8, P02281, B4DIJ7, P61964, Q9UBL3, Q15291, J3QS39, Q9C005
- Ligands
- ZN
Structure
electron microscopy · resolution 4.25 · 17 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 97 | — | A0A310TTQ1 |
| B | — | protein | 82 | — | P62799 |
| C | — | protein | 106 | — | Q6AZJ8 |
| D | — | protein | 96 | — | P02281 |
| E | — | protein | 95 | — | A0A310TTQ1 |
| F | — | protein | 79 | — | P62799 |
| G | — | protein | 105 | — | Q6AZJ8 |
| H | — | protein | 95 | — | P02281 |
| I | — | dna | 146 | — | — |
| J | — | dna | 146 | — | — |
| K | — | protein | 176 | — | B4DIJ7 |
| L | — | protein | 303 | — | P61964 |
| M | — | protein | 328 | — | Q9UBL3 |
| N | — | protein | 366 | — | Q15291 |
| O | — | protein | 75 | — | J3QS39 |
| P | — | protein | 52 | — | Q9C005 |
| Q | — | protein | 51 | — | Q9C005 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains K
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P62799 · AlphaFold monomer V2.0 prediction for histone H4 (P62799) · a predicted model of the same protein · chain F against A, TM-score 0.95
- Q9UBL3 · AlphaFold monomer V2.0 prediction for SET1/ASH2 histone methyltransferase complex subunit… · a predicted model of the same protein · chain M against A, TM-score 0.65
- Q9C005 · AlphaFold monomer V2.0 prediction for protein dpy-30 homolog (Q9C005) · a predicted model of the same protein · chain P against A, TM-score 0.55
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A310TTQ1
- Every structure of UniProt P62799
- Every structure of UniProt Q6AZJ8
- Every structure of UniProt P02281
- Every structure of UniProt B4DIJ7
- Every structure of UniProt P61964
- Every structure of UniProt Q9UBL3
- Every structure of UniProt Q15291
- Every structure of UniProt J3QS39
- Every structure of UniProt Q9C005
- Elsewhere: RCSB PDB 7UD5 · PDBe 7UD5 · UniProt A0A310TTQ1 · UniProt P62799 · UniProt Q6AZJ8 · UniProt P02281 · UniProt B4DIJ7 · UniProt P61964 · UniProt Q9UBL3 · UniProt Q15291 · UniProt J3QS39 · UniProt Q9C005
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