UniProt Q9C005
Protein dpy-30 homolog (Q9C005)
Protein dpy-30 homolog (UniProt Q9C005): 12 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9C005
- Protein
- Protein dpy-30 homolog
- Experimental structures
- 12
- Predicted models
- 1
Structures
13 records of Q9C005 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3G36 | Crystal structure of the human DPY-30-like C-terminal domain | x-ray diffraction | A, B, C, D | — | — |
| 3G36 | Crystal structure of the human dpy-30-like C-terminal domain | x-ray diffraction | A, B, C, D | — | — |
| 4RIQ | Crystal structure of DPY-30 dimerization/docking domain in complex with Ash2L Sdc1-DPY-30… | x-ray diffraction | A, B, D, E, G, H, J, K, M, N, P, Q, S, T, V, Z | — | — |
| 4RIQ | Crystal structure of dpy-30 DIMERIZATION/DOCKING domain in complex with ASH2L SDC1-dpy-30… | x-ray diffraction | A, B, D, E, G, H, J, K, M, N, P, Q, S, T, V, Z | — | — |
| 4RT4 | Crystal structure of Dpy30 complexed with Bre2 | x-ray diffraction | A, B, C, D | — | — |
| 4RT4 | Crystal structure of DPY30 complexed with BRE2 | x-ray diffraction | A, B, C, D | — | — |
| 4RTA | Cystal structure of the Dpy30 for MLL/SET1 COMPASS H3K4 trimethylation | x-ray diffraction | A, B | — | — |
| 4RTA | Cystal structure of the DPY30 for MLL/SET1 compass H3K4 trimethylation | x-ray diffraction | A, B | — | — |
| 6E2H | Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30 | x-ray diffraction | E, F | — | — |
| 6E2H | Crystal structure of human ASH2L (spry domain and sdi motif) in complex with full length dpy-30 | x-ray diffraction | E, F | — | — |
| 6PWV | Cryo-EM structure of MLL1 core complex bound to the nucleosome | electron microscopy | E, F | — | — |
| 7UD5 | Complex between MLL1-WRAD and an H2B-ubiquitinated nucleosome | electron microscopy | P, Q | — | — |
| Q9C005 | AlphaFold monomer V2.0 prediction for protein dpy-30 homolog (Q9C005) | predicted | A | — | — |
Experiment against prediction
- 4RIQ chain P against the predicted model Q9C005: TM-score 0.98, RMSD 0.28 Å
- 4RIQ chain P against the predicted model Q9C005: TM-score 0.98, RMSD 0.28 Å
- 4RIQ chain S against the predicted model Q9C005: TM-score 0.98, RMSD 0.31 Å
- 4RIQ chain S against the predicted model Q9C005: TM-score 0.98, RMSD 0.31 Å
- 4RT4 chain B against the predicted model Q9C005: TM-score 0.98, RMSD 0.33 Å
- 4RT4 chain B against the predicted model Q9C005: TM-score 0.98, RMSD 0.33 Å
- 4RIQ chain J against the predicted model Q9C005: TM-score 0.98, RMSD 0.33 Å
- 4RIQ chain J against the predicted model Q9C005: TM-score 0.98, RMSD 0.33 Å
- 4RIQ chain M against the predicted model Q9C005: TM-score 0.98, RMSD 0.34 Å
- 4RIQ chain M against the predicted model Q9C005: TM-score 0.98, RMSD 0.34 Å
Elsewhere
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