UniProt Q15291
Retinoblastoma-binding protein 5 (Q15291)
Retinoblastoma-binding protein 5 (UniProt Q15291): 42 experimental structures on GenesisL1, 1 ligand bound, 44 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q15291
- Protein
- Retinoblastoma-binding protein 5
- Experimental structures
- 42
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 44 · 12 records with a druggable one
Structures
42 records of Q15291 in the MolNFT archive: 42 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3P4F | Structural and biochemical insights into MLL1 core complex assembly and regulation. | x-ray diffraction | B | — | — |
| 3P4F | Structural and biochemical insights into MLL1 core complex assembly and regulation. | x-ray diffraction | B | — | — |
| 4X8N | Crystal structure of Ash2L SPRY domain in complex with phosphorylated RbBP5 | x-ray diffraction | B | — | — |
| 4X8N | Crystal structure of ASH2L spry domain in complex with phosphorylated RBBP5 | x-ray diffraction | B | — | — |
| 4X8P | Crystal structure of Ash2L SPRY domain in complex with RbBP5 | x-ray diffraction | B | — | — |
| 4X8P | Crystal structure of ASH2L spry domain in complex with RBBP5 | x-ray diffraction | B | — | — |
| 5F6K | Crystal structure of the MLL3-Ash2L-RbBP5 complex | x-ray diffraction | D, F | — | — |
| 5F6K | Crystal structure of the MLL3-ASH2L-RBBP5 complex | x-ray diffraction | D, F | — | — |
| 5F6L | The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L | x-ray diffraction | J | — | — |
| 5F6L | The crystal structure of MLL1 (N3861I/Q3867L) in complex with RBBP5 and ASH2L | x-ray diffraction | J | — | — |
| 6KIU | Cryo-EM structure of human MLL1-ubNCP complex (3.2 angstrom) | electron microscopy | N | — | 5 (best 0.79) |
| 6KIU | Cryo-EM structure of human MLL1-ubncp complex (3.2 ångström) | electron microscopy | N | — | — |
| 6KIV | Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom) | electron microscopy | N | — | 7 (best 0.80) |
| 6KIV | Cryo-EM structure of human MLL1-ubncp complex (4.0 ångström) | electron microscopy | N | — | — |
| 6KIW | Cryo-EM structure of human MLL3-ubncp complex (4.0 ångström) | electron microscopy | N | — | — |
| 6KIX | Cryo-EM structure of human MLL1-NCP complex, binding mode1 | electron microscopy | N | — | — |
| 6KIX | Cryo-EM structure of human MLL1-ncp complex, binding MODE1 | electron microscopy | N | — | — |
| 6KIZ | Cryo-EM structure of human MLL1-ncp complex, binding MODE2 | electron microscopy | N | — | — |
| 6KM7 | The structural basis for the internal interaction in RBBP5 | x-ray diffraction | A, B, C, D | SO4 | — |
| 6KM7 | The structural basis for the internal interaction in RBBP5 | x-ray diffraction | A, B, C, D | SO4 | — |
| 6PWV | Cryo-EM structure of MLL1 core complex bound to the nucleosome | electron microscopy | A | — | 4 (best 0.81) |
| 6PWV | Cryo-EM structure of MLL1 core complex bound to the nucleosome | electron microscopy | A | — | — |
| 6PWW | Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome | electron microscopy | A | — | 5 (best 0.82) |
| 6PWW | Cryo-EM structure of MLL1 in complex with RBBP5 and WDR5 bound to the nucleosome | electron microscopy | A | — | — |
| 6PWX | Cryo-EM structure of RbBP5 bound to the nucleosome | electron microscopy | A | — | 3 (best 0.84) |
| 6PWX | Cryo-EM structure of RBBP5 bound to the nucleosome | electron microscopy | A | — | — |
| 6W5I | Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome… | electron microscopy | A | — | 2 (best 0.82) |
| 6W5I | Cryo-EM structure of MLL1 in complex with RBBP5, WDR5, SET1, and ASH2L bound to the nucleosome… | electron microscopy | A | — | — |
| 6W5M | Cryo-EM structure of MLL1 in complex with RBBP5, WDR5, SET1, and ASH2L bound to the nucleosome… | electron microscopy | A | — | — |
| 6W5N | Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome… | electron microscopy | A | — | 4 (best 0.81) |
| 6W5N | Cryo-EM structure of MLL1 in complex with RBBP5, WDR5, SET1, and ASH2L bound to the nucleosome… | electron microscopy | A | — | — |
| 7BRE | The crystal structure of MLL2 in complex with ASH2L and RBBP5 | x-ray diffraction | C, F | — | 4 (best 0.52) |
| 7BRE | The crystal structure of MLL2 in complex with ASH2L and RBBP5 | x-ray diffraction | C, F | — | — |
| 7MBM | Cryo-EM structure of MLL1-ncp (H3K4M) complex, MODE01 | electron microscopy | A | — | — |
| 7MBN | Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode02 | electron microscopy | A | — | 4 (best 0.81) |
| 7MBN | Cryo-EM structure of MLL1-ncp (H3K4M) complex, MODE02 | electron microscopy | A | — | — |
| 7UD5 | Complex between MLL1-WRAD and an H2B-ubiquitinated nucleosome | electron microscopy | N | — | — |
| 7W67 | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me0 peptide | x-ray diffraction | F | — | 2 (best 0.58) |
| 7W6A | Crystal structure of the MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L complex | x-ray diffraction | F | — | 1 (best 0.59) |
| 7W6I | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me1 peptide | x-ray diffraction | F | — | 3 (best 0.52) |
| 7W6L | The crystal structure of MLL3-RBBP5-ASH2L in complex with H3K4me0 peptide | x-ray diffraction | D, F | — | — |
| Q15291 | AlphaFold monomer V2.0 prediction for retinoblastoma-binding protein 5 (Q15291) | — | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Elsewhere
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