UniProt Q6AZJ8
Histone H2A (Q6AZJ8)
Histone H2A (UniProt Q6AZJ8): 171 experimental structures on GenesisL1, 4 ligands bound, 127 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q6AZJ8
- Protein
- Histone H2A
- Experimental structures
- 171
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 127 · 13 records with a druggable one
Structures
171 records of Q6AZJ8 in the MolNFT archive: 171 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1S32 | Molecular Recognition of the Nucleosomal 'Supergroove' | x-ray diffraction | C, G | — | — |
| 2NZD | Nucleosome core particle containing 145 bp of DNA | x-ray diffraction | C, G | — | — |
| 2NZD | Nucleosome core particle containing 145 bp of DNA | x-ray diffraction | C, G | — | — |
| 3B6F | Nucleosome core particle treated with cisplatin | x-ray diffraction | C, G | — | — |
| 3B6F | Nucleosome core particle treated with cisplatin | x-ray diffraction | C, G | — | — |
| 3B6G | Nucleosome core particle treated with oxaliplatin | x-ray diffraction | C, G | — | — |
| 3B6G | Nucleosome core particle treated with oxaliplatin | x-ray diffraction | C, G | — | — |
| 3KUY | DNA Stretching in the Nucleosome Facilitates Alkylation by an Intercalating Antitumor Agent | x-ray diffraction | C, G | — | — |
| 3KUY | DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumor agent | x-ray diffraction | C, G | — | — |
| 3KWQ | Structural characterization of H3K56Q nucleosomes and nucleosomal arrays | x-ray diffraction | C, G | — | — |
| 3KWQ | Structural characterization of H3K56Q nucleosomes and nucleosomal arrays | x-ray diffraction | C, G | — | — |
| 3KXB | Structural characterization of H3K56Q nucleosomes and nucleosomal arrays | x-ray diffraction | C, G | — | — |
| 3KXB | Structural characterization of H3K56Q nucleosomes and nucleosomal arrays | x-ray diffraction | C, G | — | — |
| 3LEL | Structural Insight into the Sequence-Dependence of Nucleosome Positioning | x-ray diffraction | C, G, M, Q | — | — |
| 3LEL | Structural insight into the sequence-dependence of nucleosome positioning | x-ray diffraction | C, G, M, Q | — | — |
| 3LJA | Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome | x-ray diffraction | C, G | — | — |
| 3LJA | Using soft X-rays for a detailed picture of divalent metal binding in the nucleosome | x-ray diffraction | C, G | — | — |
| 3LZ0 | Crystal Structure of Nucleosome Core Particle Composed of the Widom 601 DNA Sequence (orientation 1) | x-ray diffraction | C, G | — | — |
| 3LZ0 | Crystal structure of nucleosome core particle composed of the widom 601 DNA sequence (orientation 1) | x-ray diffraction | C, G | — | — |
| 3LZ1 | Crystal Structure of Nucleosome Core Particle Composed of the Widom 601 DNA Sequence (orientation 2) | x-ray diffraction | C, G | — | — |
| 3LZ1 | Crystal structure of nucleosome core particle composed of the widom 601 DNA sequence (orientation 2) | x-ray diffraction | C, G | — | — |
| 3MGP | Binding of Cobalt ions to the Nucleosome Core Particle | x-ray diffraction | C, G | — | — |
| 3MGP | Binding of cobalt ions to the nucleosome core particle | x-ray diffraction | C, G | — | — |
| 3MGQ | Binding of Nickel ions to the Nucleosome Core Particle | x-ray diffraction | C, G | — | — |
| 3MGQ | Binding of nickel ions to the nucleosome core particle | x-ray diffraction | C, G | — | — |
| 3MGR | Binding of Rubidium ions to the Nucleosome Core Particle | x-ray diffraction | C, G | — | — |
| 3MGR | Binding of rubidium ions to the nucleosome core particle | x-ray diffraction | C, G | — | — |
| 3MGS | Binding of Cesium ions to the Nucleosome Core particle | x-ray diffraction | C, G | — | — |
| 3MGS | Binding of cesium ions to the nucleosome core particle | x-ray diffraction | C, G | — | — |
| 3MNN | A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core | x-ray diffraction | C, G | — | — |
| 3MNN | A ruthenium antitumour agent forms specific histone protein adducts in the nucleosome core | x-ray diffraction | C, G | — | — |
| 3MVD | Crystal structure of the chromatin factor RCC1 in complex with the nucleosome core particle | x-ray diffraction | C, G | — | — |
| 3MVD | Crystal structure of the chromatin factor RCC1 in complex with the nucleosome core particle | x-ray diffraction | C, G | — | — |
| 3TU4 | Crystal structure of the Sir3 BAH domain in complex with a nucleosome core particle. | x-ray diffraction | C, G | — | — |
| 3TU4 | Crystal structure of the SIR3 bah domain in complex with a nucleosome core particle. | x-ray diffraction | C, G | — | — |
| 3UT9 | Crystal Structure of Nucleosome Core Particle Assembled with a Palindromic Widom '601' Derivative… | x-ray diffraction | C, G | — | — |
| 3UT9 | Crystal structure of nucleosome core particle assembled with a palindromic widom '601' derivative… | x-ray diffraction | C, G | — | — |
| 3UTA | Crystal Structure of Nucleosome Core Particle Assembled with an Alpha-Satellite Sequence Containing… | x-ray diffraction | C, G | — | — |
| 3UTA | Crystal structure of nucleosome core particle assembled with an alpha- satellite sequence… | x-ray diffraction | C, G | — | — |
| 3UTB | Crystal Structure of Nucleosome Core Particle Assembled with the 146b Alpha-Satellite Sequence… | x-ray diffraction | C, G | — | — |
| 3UTB | Crystal structure of nucleosome core particle assembled with the 146B alpha-satellite sequence… | x-ray diffraction | C, G | — | — |
| 4J8V | X-ray structure of NCP145 with bound chlorido(eta-6-p-cymene)(N-phenyl-2-pyridinecarbothioamide)ruth… | x-ray diffraction | C, G | — | — |
| 4J8V | X-ray structure of NCP145 with bound CHLORIDO(ETA-6-P-CYMENE)(N… | x-ray diffraction | C, G | — | — |
| 4J8W | X-ray structure of NCP145 with chlorido(eta-6-p-cymene)(N-fluorophenyl-2-pyridinecarbothioamide)osmi… | x-ray diffraction | C, G | — | — |
| 4J8W | X-ray structure of NCP145 with CHLORIDO(ETA-6-P-CYMENE)(N… | x-ray diffraction | C, G | — | — |
| 4J8X | X-ray structure of NCP145 with bound chlorido(eta-6-p-cymene)(N-fluorophenyl-2-pyridinecarbothioamid… | x-ray diffraction | C, G | — | — |
| 4J8X | X-ray structure of NCP145 with bound CHLORIDO(ETA-6-P-CYMENE)(N… | x-ray diffraction | C, G | — | — |
| 4KGC | Nucleosome Core Particle Containing (ETA6-P-CYMENE)-(1, 2-ETHYLENEDIAMINE)-RUTHENIUM | x-ray diffraction | C, G | — | — |
| 4KGC | Nucleosome core particle containing (ETA6-P-cymene)-(1, 2- ethylenediamine)-ruthenium | x-ray diffraction | C, G | — | — |
| 4KHA | Structural basis of histone H2A-H2B recognition by the essential chaperone FACT | x-ray diffraction | B | — | — |
| 4KHA | Structural basis of histone H2A-H2B recognition by the essential chaperone fact | x-ray diffraction | B | — | — |
| 4LD9 | Crystal structure of the N-terminally acetylated BAH domain of Sir3 bound to the nucleosome core… | x-ray diffraction | C, G | — | — |
| 4LD9 | Crystal structure of the N-terminally acetylated bah domain of SIR3 bound to the nucleosome core… | x-ray diffraction | C, G | — | — |
| 4R8P | Crystal structure of the Ring1B/Bmi1/UbcH5c PRC1 ubiquitylation module bound to the nucleosome core… | x-ray diffraction | C, G | — | — |
| 4R8P | Crystal structure of the RING1B/BMI1/UBCH5C PRC1 ubiquitylation module bound to the nucleosome core… | x-ray diffraction | C, G | — | — |
| 4XUJ | Nucleosome core particle containing adducts from treatment with a thiomorpholine-substituted… | x-ray diffraction | C, G | — | — |
| 4XUJ | Nucleosome core particle containing adducts from treatment with a thiomorpholine-substituted… | x-ray diffraction | C, G | — | — |
| 4XZQ | Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad… | x-ray diffraction | C, G | — | — |
| 4XZQ | Nucleosome disassembly by rsc and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad… | x-ray diffraction | C, G | — | — |
| 4YS3 | Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad… | x-ray diffraction | C, G | — | — |
111 records more on the page itself.
Ligands
Experiment against prediction
- 6PX3 chain C against the predicted model P0CH09: TM-score 0.42, RMSD 1.81 Å
- 6NZO chain C against the predicted model P0CH09: TM-score 0.31, RMSD 4.92 Å
- 6NZO chain C against the predicted model P0CH09: TM-score 0.31, RMSD 4.92 Å
- 6PX1 chain C against the predicted model P0CH09: TM-score 0.31, RMSD 4.44 Å
- 6NZO chain G against the predicted model P0CH09: TM-score 0.30, RMSD 4.48 Å
- 6NZO chain G against the predicted model P0CH09: TM-score 0.30, RMSD 4.48 Å
- 6PX3 chain G against the predicted model P0CH09: TM-score 0.30, RMSD 4.48 Å
Elsewhere
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