MolNFT v2 · #169094 · protein
Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state
6VPO: “Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state”. Electron microscopy at 4.4, 4 ligands (GTP, GDP, ANP). MolNFT v2 #169094 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6VPO
- Type
- protein
- Length
- 1,173 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 4.4
- Source
- Drosophila melanogaster; Sus scrofa
- UniProt
- P02550, P02554, P46863
- Ligands
- GTP, GDP, ANP, MG
Structure
electron microscopy · resolution 4.4 · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 422 | — | P02550 |
| B | — | protein | 421 | — | P02554 |
| C | — | protein | 330 | — | P46863 |
Ligands and binding sites
- GTP · Guanosine-5'-triphosphate · ligand · chains A, B
- GDP · Guanosine-5'-diphosphate · ligand · chains B
- ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · chains C
- MG · Magnesium ion · metal · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6VPO · Cryo-EM structure of microtubule-bound KLP61F motor domain in the amppnp state · the same entry in another collection · chain A against A, TM-score 1.00
- P02550 · AlphaFold monomer V2.0 prediction for tubulin alpha-1A chain (P02550) · a predicted model of the same protein · chain A against A, TM-score 0.97
- P46863 · AlphaFold monomer V2.0 prediction for kinesin-like protein KLP61F (P46863) · a predicted model of the same protein · chain C against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02550
- Every structure of UniProt P02554
- Every structure of UniProt P46863
- Elsewhere: RCSB PDB 6VPO · PDBe 6VPO · UniProt P02550 · UniProt P02554 · UniProt P46863
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