MolNFT v1 · #458857 · protein
AlphaFold monomer V2.0 prediction for tubulin alpha-1A chain (P02550)
P02550: “AlphaFold monomer V2.0 prediction for tubulin alpha-1A chain (P02550)”. 3 pockets (best druggability 0.65). MolNFT v1 #458857 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P02550
- Type
- protein
- Length
- 451 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf3C12C0D17117Fb2675C039f3b01b33237B9C2D1
- Molecule
- Tubulin alpha-1A chain
- UniProt
- P02550
- Pockets
- 3 · best druggability 0.65
Structure
1 distinct chain · 45% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tubulin alpha-1A chain | protein | 451 | 45% helix, 17% strand | P02550 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 197 | 0.65 | 0.85 | 34 | empty |
| 2 | 122 | 0.40 | 0.75 | 17 | empty |
| 3 | 70 | 0.33 | 0.75 | 17 | empty |
Compared structures
- 6MZG · Structural basis of tubulin recruitment and assembly by microtubule polymerases with… · an experimental structure of the same protein · chain A against I, TM-score 0.95
- 1SA1 · Tubulin-podophyllotoxin: stathmin-like domain complex · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 1SA1 · Tubulin-podophyllotoxin: stathmin-like domain complex · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 1SA0 · Tubulin-colchicine: stathmin-like domain complex · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 1SA0 · Tubulin-colchicine: stathmin-like domain complex · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 6MZE · Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases with… · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 6MZE · Structural basis of tubulin recruitment and assembly by microtubule polymerases with… · an experimental structure of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02550
- Elsewhere: UniProt P02550 · AlphaFold DB P02550
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