MolNFT v1 · #157444 · protein
Structural basis of tubulin recruitment and assembly by microtubule polymerases with tumor overexpressed gene (tog) domain arrays
6MZE: “Structural basis of tubulin recruitment and assembly by microtubule polymerases with tumor overexpressed gene…”. X-ray diffraction, 3 ligands (GTP, GDP, MG). MolNFT v1 #157444 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6MZE
- Type
- protein
- Length
- 9,981 residues
- Chains
- 28
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P02550, P02554
- Ligands
- GTP, GDP, MG
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, H, J, O, Q, V, X | — | protein | 423 | — | P02550 |
| B, D, I, K, P, R, W, Y | — | protein | 424 | — | P02554 |
| E, Z | — | protein | 492 | — | — |
| F, G, M, N, T, U, a, b | — | protein | 155 | — | — |
| L | — | protein | 491 | — | — |
| S | — | protein | 490 | — | — |
Ligands and binding sites
- GTP · Guanosine-5'-triphosphate · ligand · 8 copies · chains A, B, C, D, H, I, J, K, O, P, Q, R, V, W, X, Y
- GDP · Guanosine-5'-diphosphate · ligand · 8 copies · chains B, D, I, K, P, R, W, Y
- MG · Magnesium ion · metal · 16 copies · chains A, B, C, H, I, J, K, O, P, Q, R, V, W, X, Y
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6MZE · Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02550
- Every structure of UniProt P02554
- Elsewhere: RCSB PDB 6MZE · PDBe 6MZE · UniProt P02550 · UniProt P02554
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