MolNFT v1 · #157446 · protein
Structural basis of tubulin recruitment and assembly by microtubule polymerases with tumor overexpressed gene (tog) domain arrays
6MZG: “Structural basis of tubulin recruitment and assembly by microtubule polymerases with tumor overexpressed gene…”. X-ray diffraction, 3 ligands (GTP, GDP, MG). MolNFT v1 #157446 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6MZG
- Type
- protein
- Length
- 4,659 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P02550, P02554
- Ligands
- GTP, GDP, MG
Structure
x-ray diffraction · 9 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 427 | — | P02550 |
| B | — | protein | 430 | — | P02554 |
| C | — | protein | 433 | — | P02550 |
| D, J | — | protein | 428 | — | P02554 |
| E, K | — | protein | 487 | — | — |
| F, L | — | protein | 125 | — | — |
| G | — | protein | 425 | — | P02550 |
| H | — | protein | 429 | — | P02554 |
| I | — | protein | 435 | — | P02550 |
Ligands and binding sites
- GTP · Guanosine-5'-triphosphate · ligand · 4 copies · chains A, B, C, D, G, H, I, J
- GDP · Guanosine-5'-diphosphate · ligand · 4 copies · chains B, D, H, J
- MG · Magnesium ion · metal · 8 copies · chains A, B, C, D, G, H, I, J
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6MZG · Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases with… · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02550
- Every structure of UniProt P02554
- Elsewhere: RCSB PDB 6MZG · PDBe 6MZG · UniProt P02550 · UniProt P02554
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