Research workbench
Structural basis of tubulin recruitment and assembly by microtubule polymerases with tumor overexpressed gene (tog) domain arrays
Analyse Structural basis of tubulin recruitment and assembly by microtubule polymerases… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6MZG
- Type
- protein
- Length
- 4,659 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P02550, P02554
- Ligands
- GTP, GDP, MG
Structure
x-ray diffraction · 9 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 427 | — | P02550 |
| B | — | protein | 430 | — | P02554 |
| C | — | protein | 433 | — | P02550 |
| D, J | — | protein | 428 | — | P02554 |
| E, K | — | protein | 487 | — | — |
| F, L | — | protein | 125 | — | — |
| G | — | protein | 425 | — | P02550 |
| H | — | protein | 429 | — | P02554 |
| I | — | protein | 435 | — | P02550 |
Ligands and binding sites
- GTP · Guanosine-5'-triphosphate · ligand · 4 copies · chains A, B, C, D, G, H, I, J
- GDP · Guanosine-5'-diphosphate · ligand · 4 copies · chains B, D, H, J
- MG · Magnesium ion · metal · 8 copies · chains A, B, C, D, G, H, I, J
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6MZG · Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases with… · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02550
- Every structure of UniProt P02554
- Elsewhere: RCSB PDB 6MZG · PDBe 6MZG · UniProt P02550 · UniProt P02554
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