UniProt P46863
Kinesin-like protein Klp61F (P46863)
Kinesin-like protein Klp61F (UniProt P46863): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P46863
- Protein
- Kinesin-like protein Klp61F
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
11 records of P46863 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2WBE | Kinesin-5-Tubulin Complex with AMPPNP | electron microscopy | C | — | — |
| 2WBE | Kinesin-5-tubulin complex with amppnp | electron microscopy | C | — | — |
| 4PXT | Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers | x-ray diffraction | A, B | — | — |
| 4PXT | Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers | x-ray diffraction | A, B | — | — |
| 4PXU | Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers | x-ray diffraction | A, B | — | — |
| 4PXU | Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers | x-ray diffraction | A, B | — | — |
| 6VPO | Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state | electron microscopy | C | ANP | — |
| 6VPO | Cryo-EM structure of microtubule-bound KLP61F motor domain in the amppnp state | electron microscopy | C | ANP | — |
| 6VPP | Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state | electron microscopy | C | — | 8 (best 0.81) |
| 6VPP | Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state | electron microscopy | C | — | — |
| P46863 | AlphaFold monomer V2.0 prediction for kinesin-like protein KLP61F (P46863) | predicted | A | — | — |
Ligands
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
Experiment against prediction
- 6VPO chain C against the predicted model P46863: TM-score 0.92, RMSD 2.11 Å
- 6VPO chain C against the predicted model P46863: TM-score 0.92, RMSD 2.11 Å
- 2WBE chain C against the predicted model P46863: TM-score 0.91, RMSD 2.43 Å
- 2WBE chain C against the predicted model P46863: TM-score 0.91, RMSD 2.43 Å
- 6VPP chain C against the predicted model P46863: TM-score 0.87, RMSD 2.69 Å
- 6VPP chain C against the predicted model P46863: TM-score 0.87, RMSD 2.69 Å
- 4PXU chain B against the predicted model P46863: TM-score 0.75, RMSD 2.90 Å
- 4PXU chain B against the predicted model P46863: TM-score 0.75, RMSD 2.90 Å
- 4PXU chain A against the predicted model P46863: TM-score 0.71, RMSD 3.44 Å
- 4PXU chain A against the predicted model P46863: TM-score 0.71, RMSD 3.44 Å
Elsewhere
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