MolNFT v1 · #188219 · protein
Structure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp (proliferating cell nuclear antigen PCNA) in an autoinhibited conformation
7THJ: “Structure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp (proliferating cell…”. Electron microscopy, 3 ligands (AGS, ADP, MG). MolNFT v1 #188219 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 7THJ
- Type
- protein
- Length
- 2,554 residues
- Chains
- 8
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P38630, P40339, P38629, P40348, P38251, P15873
- Ligands
- AGS, ADP, MG
Structure
electron microscopy · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 482 | — | P38630 |
| B | — | protein | 315 | — | P40339 |
| C | — | protein | 322 | — | P38629 |
| D | — | protein | 328 | — | P40348 |
| E | — | protein | 338 | — | P38251 |
| F, H | — | protein | 256 | — | P15873 |
| G | — | protein | 257 | — | P15873 |
Ligands and binding sites
- AGS · Phosphothiophosphoric acid-adenylate ester · ligand · 4 copies · chains A, B, C, D, E
- ADP · Adenosine-5'-diphosphate · ligand · chains A, E
- MG · Magnesium ion · metal · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7THJ · Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp… · the same entry in another collection · chain G against G, TM-score 1.00
- P40339 · AlphaFold monomer V2.0 prediction for replication factor C subunit 4 (P40339) · a predicted model of the same protein · chain B against A, TM-score 0.98
- P38629 · AlphaFold monomer V2.0 prediction for replication factor C subunit 3 (P38629) · a predicted model of the same protein · chain C against A, TM-score 0.97
- P38251 · AlphaFold monomer V2.0 prediction for replication factor C subunit 5 (P38251) · a predicted model of the same protein · chain E against A, TM-score 0.97
- P40348 · AlphaFold monomer V2.0 prediction for replication factor C subunit 2 (P40348) · a predicted model of the same protein · chain D against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P38630
- Every structure of UniProt P40339
- Every structure of UniProt P38629
- Every structure of UniProt P40348
- Every structure of UniProt P38251
- Every structure of UniProt P15873
- Elsewhere: RCSB PDB 7THJ · PDBe 7THJ · UniProt P38630 · UniProt P40339 · UniProt P38629 · UniProt P40348 · UniProt P38251 · UniProt P15873
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