MolNFT v1 · #341130 · protein
AlphaFold monomer V2.0 prediction for replication factor C subunit 4 (P40339)
P40339: “AlphaFold monomer V2.0 prediction for replication factor C subunit 4 (P40339)”. 2 pockets (best druggability 0.67). MolNFT v1 #341130 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P40339
- Type
- protein
- Length
- 323 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x92C13525f7d099F9849aB1EF45113915218e2BB0
- Molecule
- Replication factor C subunit 4
- UniProt
- P40339
- Pockets
- 2 · best druggability 0.67
Structure
1 distinct chain · 61% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Replication factor C subunit 4 | protein | 323 | 61% helix, 9% strand | P40339 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 145 | 0.67 | 0.88 | 27 | empty |
| 2 | 99 | 0.36 | 0.74 | 14 | empty |
Compared structures
- 1SXJ · Crystal structure of the eukaryotic clamp loader (replication factor C, rfc) bound to the… · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 1SXJ · Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the… · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 7THJ · Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp… · an experimental structure of the same protein · chain A against B, TM-score 0.95
- 7THJ · Structure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp… · an experimental structure of the same protein · chain A against B, TM-score 0.95
- 7TIC · Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp… · an experimental structure of the same protein · chain A against B, TM-score 0.95
- 7TIC · Structure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp… · an experimental structure of the same protein · chain A against B, TM-score 0.95
- 8THB · Structure of the Saccharomyces cerevisiae PCNA clamp unloader Elg1-RFC complex · an experimental structure of the same protein · chain A against B, TM-score 0.94
- 7THV · Structure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp… · an experimental structure of the same protein · chain A against B, TM-score 0.94
- 7THV · Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp… · an experimental structure of the same protein · chain A against B, TM-score 0.94
- 8THD · Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to PCNA · an experimental structure of the same protein · chain A against B, TM-score 0.94
- 8THC · Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to a cracked PCNA · an experimental structure of the same protein · chain A against B, TM-score 0.94
- 8TW7 · Cryo-EM structure of S. cerevisiae Ctf18-RFC-PCNA complex in Apo state conformation I · an experimental structure of the same protein · chain A against 4, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40339
- Elsewhere: UniProt P40339 · AlphaFold DB P40339
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