GL1X · GenesisL1 explorer

UniProt P38630

Replication factor C subunit 1 (P38630)

Replication factor C subunit 1 (UniProt P38630): 38 experimental structures on GenesisL1, 4 ligands bound, 141 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P38630
Protein
Replication factor C subunit 1
Experimental structures
38
Predicted models
0
Ligands
4
Pockets
141 · 16 records with a druggable one

Structures

38 records of P38630 in the MolNFT archive: 38 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1SXJCrystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA…x-ray diffractionA——
1SXJCrystal structure of the eukaryotic clamp loader (replication factor C, rfc) bound to the DNA…x-ray diffractionA——
7TFIAtomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with an open…electron microscopyAAGS, MG8 (best 0.87)
7TFJAtomic model of S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with a closed clamp…electron microscopyAAGS, MG8 (best 0.85)
7TFLAtomic model of S. cerevisiae clamp loader RFC bound to DNAelectron microscopyAAGS, MG8 (best 0.84)
7THJStructure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp…electron microscopyAAGS, MG, ADP11 (best 0.87)
7THJStructure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp…electron microscopyAAGS, MG, ADP—
7THVStructure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp…electron microscopyAAGS, MG, ADP8 (best 0.89)
7THVStructure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp…electron microscopyAAGS, MG, ADP—
7TI8Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp…electron microscopyAAGS, MG, ADP7 (best 0.83)
7TI8Structure of the yeast clamp loader (replication factor C rfc) bound to the open sliding clamp…electron microscopyAAGS, MG, ADP—
7TIBStructure of the yeast clamp loader (replication factor C rfc) bound to the open sliding clamp…electron microscopyAAGS, MG, ADP—
7TICStructure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp…electron microscopyAAGS, MG, ADP—
7TIDStructure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp…electron microscopyAAGS, MG, ADP7 (best 0.88)
7TIDStructure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp…electron microscopyAAGS, MG, ADP—
7TKUStructure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp…electron microscopyAAGS, MG, ADP8 (best 0.84)
7TKUStructure of the yeast clamp loader (replication factor C rfc) bound to the open sliding clamp…electron microscopyAAGS, MG, ADP—
7U19RFC:PCNA bound to nicked DNAelectron microscopyAAGS, MG, ADP7 (best 0.80)
7U19RFC:PCNA bound to nicked DNAelectron microscopyAAGS, MG, ADP—
7U1ARFC:PCNA bound to dsDNA with a ssDNA gap of six nucleotideselectron microscopyAAGS, MG, ADP9 (best 0.87)
7U1ARFC:PCNA bound to dsdna with a ssdna gap of six nucleotideselectron microscopyAAGS, MG, ADP—
7U1PRFC:PCNA bound to DNA with a ssDNA gap of five nucleotideselectron microscopyAAGS, MG, ADP10 (best 0.88)
7U1PRFC:PCNA bound to DNA with a ssdna gap of five nucleotideselectron microscopyAAGS, MG, ADP—
8DQXOpen state of RFC:PCNA bound to a 3' ss/dsDNA junctionelectron microscopyAAGS, MG, GDP11 (best 0.85)
8DQXOpen state of RFC:PCNA bound to a 3' SS/DSDNA junctionelectron microscopyAAGS, MG, GDP—
8DQZIntermediate state of RFC:PCNA bound to a 3' SS/DSDNA junctionelectron microscopyAAGS, MG, GDP—
8DR0Closed state of RFC:PCNA bound to a 3' ss/dsDNA junctionelectron microscopyAAGS, MG, GDP8 (best 0.84)
8DR0Closed state of RFC:PCNA bound to a 3' SS/DSDNA junctionelectron microscopyAAGS, MG, GDP—
8DR1Consensus closed state of RFC:PCNA bound to a 3' SS/DSDNA junction (DNA2)electron microscopyAAGS, MG, GDP—
8DR3Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTDelectron microscopyAAGS, MG, GDP10 (best 0.82)
8DR3Closed state of RFC:PCNA bound to a 3' SS/DSDNA junction (DNA2) with ntdelectron microscopyAAGS, MG, GDP—
8DR4Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) without NTDelectron microscopyAAGS, MG, GDP11 (best 0.84)
8DR4Open state of RFC:PCNA bound to a 3' SS/DSDNA junction (DNA2) without ntdelectron microscopyAAGS, MG, GDP—
8DR5Open state of RFC:PCNA bound to a 3' SS/DSDNA junction (DNA2) with ntdelectron microscopyAMG, AGS, GDP—
8DR6Closed state of RFC:PCNA bound to a nicked dsdnaelectron microscopyAAGS, MG, ADP—
8DR7Open state of RFC:PCNA bound to a nicked dsDNAelectron microscopyAAGS, MG, GDP10 (best 0.86)
8DR7Open state of RFC:PCNA bound to a nicked dsdnaelectron microscopyAAGS, MG, GDP—
P38630AlphaFold monomer V2.0 prediction for replication factor C subunit 1 (P38630)———

Ligands

  • AGS · Phosphothiophosphoric acid-adenylate ester · in 35 records
  • MG · Magnesium ion · in 35 records
  • ADP · Adenosine-5'-diphosphate · in 19 records
  • GDP · Guanosine-5'-diphosphate · in 13 records

Elsewhere

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