GL1X · GenesisL1 explorer

MolNFT v1 · #341121 · protein

AlphaFold monomer V2.0 prediction for replication factor C subunit 3 (P38629)

P38629: “AlphaFold monomer V2.0 prediction for replication factor C subunit 3 (P38629)”. 2 pockets (best druggability 0.70). MolNFT v1 #341121 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P38629
Type
protein
Length
340 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
Molecule
Replication factor C subunit 3
UniProt
P38629
Pockets
2 · best druggability 0.70

Structure

1 distinct chain · 64% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AReplication factor C subunit 3protein34064% helix, 9% strandP38629

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11490.700.8925empty
21430.470.7718empty

Compared structures

  • 7THJ · Structure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp… · an experimental structure of the same protein · chain A against C, TM-score 0.92
  • 7TIC · Structure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp… · an experimental structure of the same protein · chain A against C, TM-score 0.92
  • 7THV · Structure of the yeast clamp loader (replication factor C rfc) bound to the sliding clamp… · an experimental structure of the same protein · chain A against C, TM-score 0.91
  • 1SXJ · Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the… · an experimental structure of the same protein · chain A against C, TM-score 0.91
  • 1SXJ · Crystal structure of the eukaryotic clamp loader (replication factor C, rfc) bound to the… · an experimental structure of the same protein · chain A against C, TM-score 0.91
  • 8THC · Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to a cracked PCNA · an experimental structure of the same protein · chain A against C, TM-score 0.90
  • 7STB · Closed state of RAD24-RFC:9-1-1 bound to a 5' SS/DSDNA junction · an experimental structure of the same protein · chain A against C, TM-score 0.90
  • 7U19 · RFC:PCNA bound to nicked DNA · an experimental structure of the same protein · chain A against C, TM-score 0.90
  • 7U1P · RFC:PCNA bound to DNA with a ssdna gap of five nucleotides · an experimental structure of the same protein · chain A against C, TM-score 0.90
  • 7TI8 · Structure of the yeast clamp loader (replication factor C rfc) bound to the open sliding… · an experimental structure of the same protein · chain A against C, TM-score 0.89
  • 8DQX · Open state of RFC:PCNA bound to a 3' SS/DSDNA junction · an experimental structure of the same protein · chain A against C, TM-score 0.89
  • 7ST9 · Open state of RAD24-RFC:9-1-1 bound to a 5' SS/DSDNA junction · an experimental structure of the same protein · chain A against C, TM-score 0.89

Analyse

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