MolNFT v1 · #162394 · protein
Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome
6R7N: “Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome”. Electron microscopy, 1 ligand (ZN). MolNFT v1 #162394 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6R7N
- Type
- protein
- Length
- 3,065 residues
- Chains
- 10
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q13098, Q9BT78, Q99627, Q15370, Q15369, Q9UNS2, Q13617, P61201
- Ligands
- ZN
Structure
electron microscopy · 10 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 419 | — | Q13098 |
| D | — | protein | 406 | — | Q9BT78 |
| H | — | protein | 169 | — | Q99627 |
| P | — | protein | 104 | — | Q15370 |
| Q | — | protein | 88 | — | Q15369 |
| R | — | protein | 86 | — | — |
| C | — | protein | 401 | — | Q9UNS2 |
| G | — | protein | 215 | — | — |
| O | — | protein | 734 | — | Q13617 |
| B | — | protein | 443 | — | P61201 |
Ligands and binding sites
- ZN · Zinc ion · metal · 3 copies · chains R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6R7N · Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome · the same entry in another collection · chain B against B, TM-score 1.00
- Q9UNS2 · AlphaFold monomer V2.0 prediction for COP9 signalosome complex subunit 3 (Q9UNS2) · a predicted model of the same protein · chain C against A, TM-score 0.97
- Q13098 · AlphaFold monomer V2.0 prediction for COP9 signalosome complex subunit 1 (Q13098) · a predicted model of the same protein · chain A against A, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13098
- Every structure of UniProt Q9BT78
- Every structure of UniProt Q99627
- Every structure of UniProt Q15370
- Every structure of UniProt Q15369
- Every structure of UniProt Q9UNS2
- Every structure of UniProt Q13617
- Every structure of UniProt P61201
- Elsewhere: RCSB PDB 6R7N · PDBe 6R7N · UniProt Q13098 · UniProt Q9BT78 · UniProt Q99627 · UniProt Q15370 · UniProt Q15369 · UniProt Q9UNS2 · UniProt Q13617 · UniProt P61201
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