UniProt Q15369
Elongin-C (Q15369)
Elongin-C (UniProt Q15369): 150 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 133 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15369
- Protein
- Elongin-C
- Experimental structures
- 150
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 133 · 30 records with a druggable one
Structures
151 records of Q15369 in the MolNFT archive: 150 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1LM8 | Structure of a HIF-1a-pVHL-ElonginB-ElonginC Complex | x-ray diffraction | C | — | — |
| 1LM8 | Structure of a hif-1A-pvhl-elonginb-elonginc complex | x-ray diffraction | C | — | — |
| 1LQB | Crystal structure of a hydroxylated HIF-1 alpha peptide bound to the pVHL/elongin-C/elongin-B… | x-ray diffraction | B | — | — |
| 1LQB | Crystal structure of a hydroxylated hif-1 alpha peptide bound to the PVHL/ELONGIN-C/ELONGIN-B… | x-ray diffraction | B | — | — |
| 1VCB | The vhl-elonginc-elonginb structure | x-ray diffraction | B, E, H, K | — | — |
| 1VCB | The vhl-elonginc-elonginb structure | x-ray diffraction | B, E, H, K | — | — |
| 2C9W | Crystal structure of socs-2 in complex with elongin-B and elongin-C at 1.9A resolution | x-ray diffraction | C | — | — |
| 2C9W | Crystal structure of socs-2 in complex with elongin-B and elongin-C at 1.9A resolution | x-ray diffraction | C | — | — |
| 2IZV | Crystal structure of socs-4 in complex with elongin-B and elongin-C at 2.55A resolution | x-ray diffraction | C | — | — |
| 2IZV | Crystal structure of socs-4 in complex with elongin-B and elongin-C at 2.55A resolution | x-ray diffraction | C | — | — |
| 2MA9 | HIV-1 Vif SOCS-box and Elongin BC solution structure | solution nmr | C | — | — |
| 2MA9 | HIV-1 vif socs-box and elongin bc solution structure | solution nmr | C | — | — |
| 3DCG | Crystal Structure of the HIV Vif BC-box in Complex with Human ElonginB and ElonginC | x-ray diffraction | B, D | — | — |
| 3DCG | Crystal structure of the HIV vif bc-box in complex with human elonginb and elonginc | x-ray diffraction | B, D | — | — |
| 3ZKJ | Crystal Structure of Ankyrin Repeat and Socs Box-Containing Protein 9 (Asb9) in Complex with… | x-ray diffraction | B, E | — | — |
| 3ZKJ | Crystal structure of ankyrin repeat and socs box-containing protein 9 (ASB9) in complex with… | x-ray diffraction | B, E | — | — |
| 3ZNG | Ankyrin repeat and SOCS-box protein 9 (ASB9) in complex with ElonginB and ElonginC | x-ray diffraction | B, E | — | — |
| 3ZNG | Ankyrin repeat and socs-box protein 9 (ASB9) in complex with elonginb and elonginc | x-ray diffraction | B, E | — | — |
| 3ZRC | pVHL54-213-EloB-EloC complex (4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)… | x-ray diffraction | B, E, H, K | — | — |
| 3ZRC | PVHL54-213-elob-eloc complex (4R)-4-hydroxy-1-[(3-methylisoxazol-5… | x-ray diffraction | B, E, H, K | — | — |
| 3ZRF | pVHL54-213-EloB-EloC complex_apo | x-ray diffraction | B, E, H, K | — | — |
| 3ZRF | PVHL54-213-elob-eloc COMPLEX_APO | x-ray diffraction | B, E, H, K | — | — |
| 3ZTC | pVHL54-213-EloB-EloC complex _ (2S,4R)-N-((1,1'-biphenyl)-4-ylmethyl)… | x-ray diffraction | B, E, H, K | — | — |
| 3ZTC | PVHL54-213-elob-eloc complex _ (2S,4R)-N-((1,1'-biphenyl)-4-ylmethyl)… | x-ray diffraction | B, E, H, K | — | — |
| 3ZTD | pVHL54-213-EloB-EloC complex _ methyl 4-(((2S,4R)-4-hydroxy-1-(2-(3… | x-ray diffraction | B, E, H, K | — | — |
| 3ZTD | PVHL54-213-elob-eloc complex _ methyl 4-(((2S,4R)-4-hydroxy… | x-ray diffraction | B, E, H, K | — | — |
| 3ZUN | pVHL54-213-EloB-EloC complex_(2S,4R)-4-hydroxy-1-(2-(3-methylisoxazol… | x-ray diffraction | B, E, H, K | — | — |
| 3ZUN | PVHL54-213-elob-eloc COMPLEX_(2S,4R)-4-hydroxy-1-(2-(3-methylisoxazol… | x-ray diffraction | B, E, H, K | — | — |
| 4AJY | von Hippel-Lindau protein-ElonginB-ElonginC complex, bound to Hif1- alpha peptide | x-ray diffraction | C | — | — |
| 4AJY | Von hippel-lindau protein-elonginb-elonginc complex, bound to HIF1- alpha peptide | x-ray diffraction | C | — | — |
| 4AWJ | pVHL:EloB:EloC complex, in complex with capped Hydroxyproline | x-ray diffraction | B, E, H, K | — | — |
| 4AWJ | PVHL:ELOB:ELOC complex, in complex with capped hydroxyproline | x-ray diffraction | B, E, H, K | — | — |
| 4B95 | pVHL-EloB-EloB-EloC complex_(2S,4R)-1-(2-chlorophenyl)carbonyl-N-[(4-chlorophenyl)methyl]-4-oxidanyl… | x-ray diffraction | B, E, H, K | — | — |
| 4B95 | Pvhl-elob-elob-eloc COMPLEX_(2S,4R)-1-(2-CHLOROPHENYL)CARBONYL-N-[(4… | x-ray diffraction | B, E, H, K | — | — |
| 4B9K | pVHL-ELOB-ELOC complex_(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benz… | x-ray diffraction | B, E, H, K | — | — |
| 4B9K | Pvhl-elob-eloc COMPLEX_(2S,4R)-1-(3-amino-2-methylbenzoyl)-4… | x-ray diffraction | B, E, H, K | — | — |
| 4BKS | von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with… | x-ray diffraction | B, E, H, K | — | — |
| 4BKS | Von hippel lindau PROTEIN:ELONGINB:ELONGINC complex, in complex with… | x-ray diffraction | B, E, H, K | — | — |
| 4BKT | von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with… | x-ray diffraction | B, E, H, K | — | — |
| 4BKT | Von hippel lindau PROTEIN:ELONGINB:ELONGINC complex, in complex with… | x-ray diffraction | B, E, H, K | — | — |
| 4N9F | Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex | x-ray diffraction | Y, E, K, Q, Z, h, n, t, z, 5, T, B | — | — |
| 4N9F | Crystal structure of the vif-cbfbeta-CUL5-elob-eloc pentameric complex | x-ray diffraction | Y, E, K, Q, Z, h, n, t, z, 5, T, B | — | — |
| 4W9C | pVHL:EloB:EloC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(oxazol-5-yl)benzyl)p… | x-ray diffraction | B, E, H, K | — | — |
| 4W9C | PVHL:ELOB:ELOC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4… | x-ray diffraction | B, E, H, K | — | — |
| 4W9D | pVHL:EloB:EloC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methyloxazol-5-yl)… | x-ray diffraction | B, E, H, K | — | — |
| 4W9D | PVHL:ELOB:ELOC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4… | x-ray diffraction | B, E, H, K | — | — |
| 4W9E | pVHL:EloB:EloC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(thiazol-5-yl)benzyl)… | x-ray diffraction | B, E, H, K | — | — |
| 4W9E | PVHL:ELOB:ELOC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4… | x-ray diffraction | B, E, H, K | — | — |
| 4W9F | pVHL:EloB:EloC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl… | x-ray diffraction | B, E, H, K | — | — |
| 4W9F | PVHL:ELOB:ELOC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4… | x-ray diffraction | B, E, H, K | — | — |
| 4W9G | pVHL:EloB:EloC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-(3-methyl-4-(thiazol-5-y… | x-ray diffraction | B, E, H, K | — | — |
| 4W9G | PVHL:ELOB:ELOC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4… | x-ray diffraction | B, E, H, K | — | — |
| 4W9H | pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-acetamido-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-me… | x-ray diffraction | B, E, H, K | — | — |
| 4W9H | PVHL:ELOB:ELOC in complex with (2S,4R)-1-((S)-2-acetamido-3,3… | x-ray diffraction | B, E, H, K | — | — |
| 4W9I | pVHL:EloB:EloC in complex with (2S,4R)-1-((2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carbonyl)-4-hydrox… | x-ray diffraction | B, E, H, K | — | — |
| 4W9I | PVHL:ELOB:ELOC in complex with (2S,4R)-1-((2S,4R)-1-acetyl-4… | x-ray diffraction | B, E, H, K | — | — |
| 4W9J | pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-((S)-2-acetamido-4-methylpentanamido)-3,3-dimethylbu… | x-ray diffraction | B, E, H, K | — | — |
| 4W9J | PVHL:ELOB:ELOC in complex with (2S,4R)-1-((S)-2-((S)-2-acetamido-4… | x-ray diffraction | B, E, H, K | — | — |
| 4W9K | pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-((S)-2-acetamido-3-phenylpropanamido)-3,3-dimethylbu… | x-ray diffraction | B, E, H, K | — | — |
| 4W9K | PVHL:ELOB:ELOC in complex with (2S,4R)-1-((S)-2-((S)-2-acetamido-3… | x-ray diffraction | B, E, H, K | — | — |
91 records more on the page itself.
Ligands
Experiment against prediction
- 2C9W chain C against the predicted model Q15369: TM-score 0.99, RMSD 0.33 Å
- 2C9W chain C against the predicted model Q15369: TM-score 0.99, RMSD 0.33 Å
- 7ZLM chain F against the predicted model Q15369: TM-score 0.99, RMSD 0.37 Å
- 2IZV chain C against the predicted model Q15369: TM-score 0.99, RMSD 0.37 Å
- 2IZV chain C against the predicted model Q15369: TM-score 0.99, RMSD 0.37 Å
- 7JTP chain K against the predicted model Q15369: TM-score 0.99, RMSD 0.38 Å
- 4W9K chain B against the predicted model Q15369: TM-score 0.99, RMSD 0.40 Å
- 4W9K chain B against the predicted model Q15369: TM-score 0.99, RMSD 0.40 Å
- 7S4E chain C against the predicted model Q15369: TM-score 0.99, RMSD 0.48 Å
- 7ZLM chain C against the predicted model Q15369: TM-score 0.99, RMSD 0.42 Å
Elsewhere
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