UniProt Q13098
COP9 signalosome complex subunit 1 (Q13098)
COP9 signalosome complex subunit 1 (UniProt Q13098): 17 experimental structures and 1 predicted model on GenesisL1, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13098
- Protein
- COP9 signalosome complex subunit 1
- Experimental structures
- 17
- Predicted models
- 1
- Pockets
- 27 · 7 records with a druggable one
Structures
18 records of Q13098 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4D10 | Crystal structure of the COP9 signalosome | x-ray diffraction | A, I | — | — |
| 4D10 | Crystal structure of the COP9 signalosome | x-ray diffraction | A, I | — | — |
| 4D18 | Crystal structure of the COP9 signalosome | x-ray diffraction | A, I | — | — |
| 4D18 | Crystal structure of the COP9 signalosome | x-ray diffraction | A, I | — | — |
| 4WSN | Crystal structure of the COP9 signalosome, a P1 crystal form | x-ray diffraction | A, I, Q, Y, g, o | — | — |
| 6R6H | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | A | — | 3 (best 0.75) |
| 6R6H | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | A | — | — |
| 6R7F | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | A | — | 1 (best 0.59) |
| 6R7F | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | A | — | — |
| 6R7H | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | A | — | 6 (best 0.68) |
| 6R7H | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | A | — | — |
| 6R7I | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | A | — | 5 (best 0.86) |
| 6R7I | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | A | — | — |
| 6R7N | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | A | — | 6 (best 0.75) |
| 6R7N | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | A | — | — |
| 8H3A | Cryo-EM Structure of the KBTBD2-CRL3~N8(removed)-CSN complex | electron microscopy | A | — | 4 (best 0.85) |
| 8H3F | Cryo-EM Structure of the KBTBD2-CRL3-CSN complex | electron microscopy | A | — | 2 (best 0.83) |
| Q13098 | AlphaFold monomer V2.0 prediction for COP9 signalosome complex subunit 1 (Q13098) | predicted | A | — | — |
Experiment against prediction
- 4D18 chain I against the predicted model Q13098: TM-score 0.92, RMSD 2.40 Å
- 4D18 chain I against the predicted model Q13098: TM-score 0.92, RMSD 2.40 Å
- 4D18 chain A against the predicted model Q13098: TM-score 0.92, RMSD 2.32 Å
- 4D18 chain A against the predicted model Q13098: TM-score 0.92, RMSD 2.32 Å
- 8H3F chain A against the predicted model Q13098: TM-score 0.92, RMSD 2.38 Å
- 4D10 chain I against the predicted model Q13098: TM-score 0.92, RMSD 2.30 Å
- 4D10 chain I against the predicted model Q13098: TM-score 0.92, RMSD 2.30 Å
- 8H3A chain A against the predicted model Q13098: TM-score 0.92, RMSD 2.34 Å
- 4WSN chain g against the predicted model Q13098: TM-score 0.92, RMSD 2.31 Å
- 4WSN chain o against the predicted model Q13098: TM-score 0.92, RMSD 2.34 Å
Elsewhere
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