UniProt Q9BT78
COP9 signalosome complex subunit 4 (Q9BT78)
COP9 signalosome complex subunit 4 (UniProt Q9BT78): 20 experimental structures and 1 predicted model on GenesisL1, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BT78
- Protein
- COP9 signalosome complex subunit 4
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 36 · 8 records with a druggable one
Structures
21 records of Q9BT78 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4D0P | Crystal structure of human CSN4 | x-ray diffraction | A | — | — |
| 4D0P | Crystal structure of human CSN4 | x-ray diffraction | A | — | — |
| 4D10 | Crystal structure of the COP9 signalosome | x-ray diffraction | D, L | — | — |
| 4D10 | Crystal structure of the COP9 signalosome | x-ray diffraction | D, L | — | — |
| 4D18 | Crystal structure of the COP9 signalosome | x-ray diffraction | D, L | — | — |
| 4D18 | Crystal structure of the COP9 signalosome | x-ray diffraction | D, L | — | — |
| 4WSN | Crystal structure of the COP9 signalosome, a P1 crystal form | x-ray diffraction | D, L, T, b, j, r | — | — |
| 6R6H | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | D | — | 6 (best 0.81) |
| 6R6H | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | D | — | — |
| 6R7F | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | D | — | 6 (best 0.73) |
| 6R7F | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | D | — | — |
| 6R7H | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | D | — | 7 (best 0.86) |
| 6R7H | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | D | — | — |
| 6R7I | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | D | — | 5 (best 0.87) |
| 6R7I | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | D | — | — |
| 6R7N | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | D | — | 3 (best 0.87) |
| 6R7N | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | D | — | — |
| 8H38 | Cryo-EM Structure of the KBTBD2-CRL3~N8-CSN(mutate) complex | electron microscopy | D | — | 3 (best 0.79) |
| 8H3A | Cryo-EM Structure of the KBTBD2-CRL3~N8(removed)-CSN complex | electron microscopy | D | — | 2 (best 0.85) |
| 8H3F | Cryo-EM Structure of the KBTBD2-CRL3-CSN complex | electron microscopy | D | — | 4 (best 0.83) |
| Q9BT78 | AlphaFold monomer V2.0 prediction for COP9 signalosome complex subunit 4 (Q9BT78) | predicted | A | — | — |
Experiment against prediction
- 4D0P chain A against the predicted model Q9BT78: TM-score 0.96, RMSD 0.92 Å
- 4D0P chain A against the predicted model Q9BT78: TM-score 0.96, RMSD 0.92 Å
- 8H38 chain D against the predicted model Q9BT78: TM-score 0.87, RMSD 1.86 Å
- 8H3F chain D against the predicted model Q9BT78: TM-score 0.87, RMSD 1.85 Å
- 8H3A chain D against the predicted model Q9BT78: TM-score 0.87, RMSD 1.77 Å
- 6R7I chain D against the predicted model Q9BT78: TM-score 0.86, RMSD 1.93 Å
- 6R7I chain D against the predicted model Q9BT78: TM-score 0.86, RMSD 1.93 Å
- 4D18 chain L against the predicted model Q9BT78: TM-score 0.86, RMSD 2.08 Å
- 4D18 chain L against the predicted model Q9BT78: TM-score 0.86, RMSD 2.08 Å
- 4D18 chain D against the predicted model Q9BT78: TM-score 0.86, RMSD 2.12 Å
Elsewhere
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