MolNFT v1 · #155697 · protein
Cryo-EM structure of a class a GPCR monomer
6LFO: “Cryo-EM structure of a class a GPCR monomer”. Electron microscopy, 1 ligand (CLR). MolNFT v1 #155697 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LFO
- Type
- protein
- Length
- 1,228 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P63096, P62873, P59768, P10145, P25025
- Ligands
- CLR
Structure
electron microscopy · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 230 | — | P63096 |
| B | — | protein | 338 | — | P62873 |
| C | — | protein | 57 | — | P59768 |
| D | — | protein | 64 | — | P10145 |
| R | — | protein | 307 | — | P25025 |
| S | — | protein | 232 | — | — |
Ligands and binding sites
- CLR · Cholesterol · ligand · chains R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6LFO · Cryo-EM structure of a class A GPCR monomer · the same entry in another collection · chain S against S, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain C against A, TM-score 0.93
- P25025 · AlphaFold monomer V2.0 prediction for C-X-C chemokine receptor type 2 (P25025) · a predicted model of the same protein · chain R against A, TM-score 0.90
- P10145 · AlphaFold monomer V2.0 prediction for interleukin-8 (P10145) · a predicted model of the same protein · chain D against A, TM-score 0.85
- P63096 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63096
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Every structure of UniProt P10145
- Every structure of UniProt P25025
- Elsewhere: RCSB PDB 6LFO · PDBe 6LFO · UniProt P63096 · UniProt P62873 · UniProt P59768 · UniProt P10145 · UniProt P25025
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