UniProt P25025
Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera (P25025)
Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera (UniProt P25025): 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, druggability and…
- UniProt
- P25025
- Protein
- Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2…
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 1 · 1 record with a druggable one
Structures
13 records of P25025 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4MPA | Crystal structure of NHERF1-CXCR2 signaling complex in P21 space group | x-ray diffraction | A | — | — |
| 4MPA | Crystal structure of NHERF1-CXCR2 signaling complex in P21 space group | x-ray diffraction | A | — | — |
| 4Q3H | The crystal structure of NHERF1 PDZ2 CXCR2 complex revealed by the NHERF1 CXCR2 chimeric protein | x-ray diffraction | A, B | — | — |
| 4Q3H | The crystal structure of NHERF1 PDZ2 CXCR2 complex revealed by the NHERF1 CXCR2 chimeric protein | x-ray diffraction | A, B | — | — |
| 5TYT | Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide | x-ray diffraction | A, B, C, D | — | 1 (best 0.76) |
| 5TYT | Crystal structure of the PDZ domain of rhogef bound to CXCR2 C- terminal peptide | x-ray diffraction | A, B, C, D | — | — |
| 6KVA | Structure of anti-HCXCR2 ABN48-2 in complex with its CXCR2 epitope | x-ray diffraction | B, b | — | — |
| 6KVF | Structure of anti-HCXCR2 ABN48 in complex with its CXCR2 epitope | x-ray diffraction | b, B | — | — |
| 6LFL | Crystal structure of a class a GPCR | x-ray diffraction | A | EBX | — |
| 6LFM | Cryo-EM structure of a class a GPCR | electron microscopy | R | CLR | — |
| 6LFO | Cryo-EM structure of a class A GPCR monomer | electron microscopy | R | CLR | — |
| 6LFO | Cryo-EM structure of a class a GPCR monomer | electron microscopy | R | CLR | — |
| P25025 | AlphaFold monomer V2.0 prediction for C-X-C chemokine receptor type 2 (P25025) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5TYT chain C against the predicted model O15085: TM-score 0.92, RMSD 1.46 Å
- 5TYT chain C against the predicted model O15085: TM-score 0.92, RMSD 1.46 Å
- 5TYT chain A against the predicted model O15085: TM-score 0.91, RMSD 1.68 Å
- 5TYT chain A against the predicted model O15085: TM-score 0.91, RMSD 1.68 Å
- 6LFO chain R against the predicted model P25025: TM-score 0.90, RMSD 2.45 Å
- 6LFO chain R against the predicted model P25025: TM-score 0.90, RMSD 2.45 Å
- 6LFM chain R against the predicted model P25025: TM-score 0.90, RMSD 2.46 Å
- 5TYT chain B against the predicted model O15085: TM-score 0.89, RMSD 1.37 Å
- 5TYT chain B against the predicted model O15085: TM-score 0.89, RMSD 1.37 Å
- 5TYT chain D against the predicted model O15085: TM-score 0.89, RMSD 1.56 Å
Elsewhere
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