UniProt P10145
P10145
P10145 (UniProt P10145): 31 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P10145
- Experimental structures
- 31
- Predicted models
- 1
Structures
32 records of P10145 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ICW | Interleukin-8, mutant with glu 38 replaced by cys and cys 50 replaced by ala | x-ray diffraction | A, B | — | — |
| 1ICW | Interleukin-8, mutant with glu 38 replaced by cys and cys 50 replaced by ala | x-ray diffraction | A, B | — | — |
| 1IKL | NMR study of monomeric human interleukin-8 (minimized average structure) | solution nmr | A | — | — |
| 1IKL | NMR study of monomeric human interleukin-8 (minimized average structure) | solution nmr | A | — | — |
| 1IKM | NMR study of monomeric human interleukin-8 (30 structures) | solution nmr | A | — | — |
| 1IKM | NMR study of monomeric human interleukin-8 (30 structures) | solution nmr | A | — | — |
| 1IL8 | Three-dimensional structure of interleukin 8 in solution | solution nmr | A, B | — | — |
| 1IL8 | Three-dimensional structure of interleukin 8 in solution | solution nmr | A, B | — | — |
| 1ILP | Cxcr-1 N-terminal peptide bound to interleukin-8 | solution nmr | A, B | — | — |
| 1ILP | Cxcr-1 N-terminal peptide bound to interleukin-8 | solution nmr | A, B | — | — |
| 1ILQ | Cxcr-1 N-terminal peptide bound to interleukin-8 (minimized mean) | solution nmr | A, B | — | — |
| 1ILQ | Cxcr-1 N-terminal peptide bound to interleukin-8 (minimized mean) | solution nmr | A, B | — | — |
| 1QE6 | Interleukin-8 with an added disulfide between residues 5 and 33 (L5C/H33C) | x-ray diffraction | A, B, C, D | — | — |
| 1QE6 | Interleukin-8 with an added disulfide between residues 5 and 33 (L5C/H33C) | x-ray diffraction | A, B, C, D | — | — |
| 1ROD | Chimeric protein of interleukin 8 and human melanoma growth stimulating activity protein, NMR | solution nmr | A, B | — | — |
| 1ROD | Chimeric protein of interleukin 8 and human melanoma growth stimulating activity protein, NMR | solution nmr | A, B | — | — |
| 2IL8 | Three-dimensional structure of interleukin 8 in solution | solution nmr | A, B | — | — |
| 2IL8 | Three-dimensional structure of interleukin 8 in solution | solution nmr | A, B | — | — |
| 3IL8 | Crystal structure of interleukin 8: symbiosis of NMR and crystallography | x-ray diffraction | A | — | — |
| 3IL8 | Crystal structure of interleukin 8: symbiosis of NMR and crystallography | x-ray diffraction | A | — | — |
| 4XDX | The crystal structure of soluble human interleukin 8 expressed in Pichia pastoris | x-ray diffraction | A | — | — |
| 4XDX | The crystal structure of soluble human interleukin 8 expressed in pichia pastoris | x-ray diffraction | A | — | — |
| 5D14 | The atomic resolution crystal structure of human IL-8 | x-ray diffraction | A | — | — |
| 5D14 | The atomic resolution crystal structure of human il-8 | x-ray diffraction | A | — | — |
| 5WDZ | Structure of monomeric interleukin-8 (1-66) | solution nmr | A | — | — |
| 6LFM | Cryo-EM structure of a class a GPCR | electron microscopy | D, E | — | — |
| 6LFO | Cryo-EM structure of a class A GPCR monomer | electron microscopy | D | — | — |
| 6LFO | Cryo-EM structure of a class a GPCR monomer | electron microscopy | D | — | — |
| 6N2U | Il-8 structure from bacterial expression source | x-ray diffraction | A | — | — |
| 6WZM | LY3041658 Fab bound to CXCL8 | x-ray diffraction | E, F | — | — |
| 6XMN | Solution NMR CXCL8-CXCR1 N-domain complex structure | solution nmr | A | — | — |
| P10145 | AlphaFold monomer V2.0 prediction for interleukin-8 (P10145) | predicted | A | — | — |
Experiment against prediction
- 1QE6 chain C against the predicted model P10145: TM-score 0.96, RMSD 0.59 Å
- 1QE6 chain C against the predicted model P10145: TM-score 0.96, RMSD 0.59 Å
- 3IL8 chain A against the predicted model P10145: TM-score 0.94, RMSD 0.88 Å
- 3IL8 chain A against the predicted model P10145: TM-score 0.94, RMSD 0.88 Å
- 1QE6 chain B against the predicted model P10145: TM-score 0.93, RMSD 1.15 Å
- 1QE6 chain B against the predicted model P10145: TM-score 0.93, RMSD 1.15 Å
- 1ICW chain B against the predicted model P10145: TM-score 0.92, RMSD 0.96 Å
- 1ICW chain B against the predicted model P10145: TM-score 0.92, RMSD 0.96 Å
- 5D14 chain A against the predicted model P10145: TM-score 0.92, RMSD 1.10 Å
- 5D14 chain A against the predicted model P10145: TM-score 0.92, RMSD 1.10 Å
Elsewhere
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