MolNFT v1 · #147142 · protein
Cryo-EM structure of the active, gs-protein complexed, human cgrp receptor
6E3Y: “Cryo-EM structure of the active, gs-protein complexed, human cgrp receptor”. Electron microscopy, 1 ligand (NH2). MolNFT v1 #147142 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6E3Y
- Type
- protein
- Length
- 1,194 residues
- Chains
- 7
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P06881, P63092, P62873, P59768, Q16602, O60894
- Ligands
- NH2
Structure
electron microscopy · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| P | — | protein | 34 | — | P06881 |
| N | — | protein | 126 | — | — |
| A | — | protein | 188 | — | P63092 |
| B | — | protein | 336 | — | P62873 |
| G | — | protein | 49 | — | P59768 |
| R | — | protein | 346 | — | Q16602 |
| E | — | protein | 115 | — | O60894 |
Ligands and binding sites
- NH2 · Amino group · ion · chains P, R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6E3Y · Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor · the same entry in another collection · chain E against E, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- O60894 · AlphaFold monomer V2.0 prediction for receptor activity-modifying protein 1 (O60894) · a predicted model of the same protein · chain E against A, TM-score 0.98
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.92
- P06881 · AlphaFold monomer V2.0 prediction for calcitonin gene-related peptide 1 (P06881) · a predicted model of the same protein · chain P against A, TM-score 0.91
- Q16602 · AlphaFold monomer V2.0 prediction for calcitonin gene-related peptide type 1 receptor… · a predicted model of the same protein · chain R against A, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06881
- Every structure of UniProt P63092
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Every structure of UniProt Q16602
- Every structure of UniProt O60894
- Elsewhere: RCSB PDB 6E3Y · PDBe 6E3Y · UniProt P06881 · UniProt P63092 · UniProt P62873 · UniProt P59768 · UniProt Q16602 · UniProt O60894
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