UniProt P06881
Calcitonin gene-related peptide 1 (P06881)
Calcitonin gene-related peptide 1 (UniProt P06881): 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P06881
- Protein
- Calcitonin gene-related peptide 1
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 3 records with a druggable one
Structures
6 records of P06881 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6E3Y | Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor | electron microscopy | P | — | 4 (best 0.67) |
| 6E3Y | Cryo-EM structure of the active, gs-protein complexed, human cgrp receptor | electron microscopy | P | NH2 | — |
| 7KNU | CryoEM structure of the CGRP receptor with bound CGRP peptide in a detergent micelle | electron microscopy | P | — | 2 (best 0.51) |
| 7KNU | Cryoem structure of the cgrp receptor with bound cgrp peptide in a detergent micelle | electron microscopy | P | — | — |
| 9AUC | Human Amylin1 Receptor in Complex with Gs and human Calcitonin Gene-Related Peptide | electron microscopy | P | PLM | 4 (best 0.70) |
| P06881 | AlphaFold monomer V2.0 prediction for calcitonin gene-related peptide 1 (P06881) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6E3Y chain P against the predicted model P06881: TM-score 0.91, RMSD 0.53 Å
- 6E3Y chain P against the predicted model P06881: TM-score 0.91, RMSD 0.53 Å
- 9AUC chain P against the predicted model P06881: TM-score 0.82, RMSD 0.86 Å
- 7KNU chain P against the predicted model P06881: TM-score 0.51, RMSD 0.77 Å
- 7KNU chain P against the predicted model P06881: TM-score 0.51, RMSD 0.77 Å
Elsewhere
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