Research workbench
Serotonin 4 (5-HT4) receptor-gs-NB35 complex
Analyse Serotonin 4 (5-HT4) receptor-gs-NB35 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7XT8
- Type
- protein
- Length
- 1,055 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P63092, P62873, P59768, P0ABE7, Q13639
- Ligands
- CLR, PLM, SRO
Structure
electron microscopy · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 238 | — | P63092 |
| B | — | protein | 338 | — | P62873 |
| G | — | protein | 57 | — | P59768 |
| N | — | protein | 128 | — | — |
| R | — | protein | 294 | — | P0ABE7, Q13639 |
Ligands and binding sites
- CLR · Cholesterol · ligand · 5 copies · chains R
- PLM · Palmitic acid · ligand · 2 copies · chains R
- SRO · Serotonin · ligand · chains R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7XT8 · Serotonin 4 (5-HT4) receptor-Gs-Nb35 complex · the same entry in another collection · chain R against R, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.93
- Q13639 · AlphaFold monomer V2.0 prediction for 5-hydroxytryptamine receptor 4 (Q13639) · a predicted model of the same protein · chain R against A, TM-score 0.91
- P0ABE7 · AlphaFold monomer V2.0 prediction for soluble cytochrome B562 (P0ABE7) · a predicted model of the same protein · chain R against A, TM-score 0.26
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63092
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Every structure of UniProt P0ABE7
- Every structure of UniProt Q13639
- Elsewhere: RCSB PDB 7XT8 · PDBe 7XT8 · UniProt P63092 · UniProt P62873 · UniProt P59768 · UniProt P0ABE7 · UniProt Q13639
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