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Pth-bound human PTH1R in complex with gs (CLASS5)

Analyse Pth-bound human PTH1R in complex with gs (CLASS5) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7VVO
Type
protein
Length
1,059 residues
Chains
6
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P63092, P54311, P63212, P01270, Q03431

Structure

electron microscopy · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein230—P63092
B—protein338—P54311
G—protein56—P63212
N—protein128——
P—protein5—P01270
R—protein302—Q03431

Compared structures

  • 7VVO · PTH-bound human PTH1R in complex with Gs (class5) · the same entry in another collection · chain R against R, TM-score 1.00
  • P54311 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
  • Q03431 · AlphaFold monomer V2.0 prediction for parathyroid HORMONE/PARATHYROID hormone-related… · a predicted model of the same protein · chain R against A, TM-score 0.92
  • P01270 · AlphaFold monomer V2.0 prediction for parathyroid hormone (P01270) · a predicted model of the same protein · chain P against A, TM-score 0.85
  • P63212 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.66

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