GL1X · GenesisL1 explorer

Research workbench

Cytochrome C oxidase structure in P-state

Analyse Cytochrome C oxidase structure in P-state in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7ATE
Type
protein
Length
1,098 residues
Chains
4
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P98002, P08306, P06030, P77921
Ligands
HEA, PEO, CUA, PC1, PGV, MN, CU, CA

Structure

electron microscopy · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein537—P98002
B—protein251—P08306
C—protein269—P06030
D—protein41—P77921

Ligands and binding sites

  • HEA · Heme-A · ligand · 2 copies · chains A, B
  • PEO · Hydrogen peroxide · ligand · chains A
  • CUA · Dinuclear copper ion · ligand · chains B
  • PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · ligand · chains A, C, D
  • PGV · (1R)-2-{[{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11E)-octadec-11-enoate · ligand · chains A, C
  • MN · Manganese (II) ion · metal · chains A, B
  • CU · Copper (II) ion · metal · chains A
  • CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7ATE · Cytochrome c oxidase structure in P-state · the same entry in another collection · chain D against D, TM-score 1.00
  • P98002 · AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 1-beta (P98002) · a predicted model of the same protein · chain A against A, TM-score 1.00
  • P08306 · AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 2 (P08306) · a predicted model of the same protein · chain B against A, TM-score 0.99
  • P06030 · AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 3 (P06030) · a predicted model of the same protein · chain C against A, TM-score 0.99
  • P77921 · AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 4 (P77921) · a predicted model of the same protein · chain D against A, TM-score 0.93

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.